[HTML][HTML] The world federation of ADHD international consensus statement: 208 evidence-based conclusions about the disorder

SV Faraone, T Banaschewski, D Coghill… - … & biobehavioral reviews, 2021 - Elsevier
Background Misconceptions about ADHD stigmatize affected people, reduce credibility of
providers, and prevent/delay treatment. To challenge misconceptions, we curated findings …

Alcohol use disorders and ADHD

M Luderer, JAR Quiroga, SV Faraone… - Neuroscience & …, 2021 - Elsevier
Despite a growing literature on the complex bidirectional relationship of ADHD and
substance use, reviews specifically focusing on alcohol are scarce. ADHD and AUD show a …

Review of rodent models of attention deficit hyperactivity disorder

SL Regan, MT Williams, CV Vorhees - Neuroscience & Biobehavioral …, 2022 - Elsevier
Attention deficit hyperactivity disorder (ADHD) is a polygenic neurodevelopmental disorder
that affects 8–12% of children and> 4% of adults. Environmental factors are believed to …

The role of iron and zinc in the treatment of adhd among children and adolescents: A systematic review of randomized clinical trials

R Granero, A Pardo-Garrido, IL Carpio-Toro… - Nutrients, 2021 - mdpi.com
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder common
from childhood to adulthood, affecting 5% to 12% among the general population in …

ADGRL1 haploinsufficiency causes a variable spectrum of neurodevelopmental disorders in humans and alters synaptic activity and behavior in a mouse model

A Vitobello, B Mazel, VG Lelianova, A Zangrandi… - The American Journal of …, 2022 - cell.com
Summary ADGRL1 (latrophilin 1), a well-characterized adhesion G protein-coupled
receptor, has been implicated in synaptic development, maturation, and activity. However …

Rodent models of attention-deficit hyperactivity disorder: An updated framework for model validation and therapeutic drug discovery

KM Kantak - Pharmacology Biochemistry and Behavior, 2022 - Elsevier
There are over twenty rodent models of Attention-Deficit Hyperactivity Disorder (ADHD), with
most reflecting a recognized ADHD subtype. Of these, only five rat models (Neonatal 6 …

An alzheimer's disease patient-derived olfactory stem cell model identifies gene expression changes associated with cognition

LM Rantanen, M Bitar, R Lampinen, R Stewart, H Quek… - Cells, 2022 - mdpi.com
An early symptom of Alzheimer's disease (AD) is an impaired sense of smell, for which the
molecular basis remains elusive. Here, we generated human olfactory neurosphere-derived …

Machine Learning Prediction of ADHD Severity: Association and Linkage to ADGRL3, DRD4, and SNAP25

ML Cervantes-Henríquez… - Journal of Attention …, 2022 - journals.sagepub.com
Objective: To investigate whether single nucleotide polymorphisms (SNPs) in the ADGRL3,
DRD4, and SNAP25 genes are associated with and predict ADHD severity in families from a …

Novel non-stimulants rescue hyperactive phenotype in an adgrl3.1 mutant zebrafish model of ADHD

HS Sveinsdóttir, C Christensen… - …, 2023 - nature.com
ADHD is a highly prevalent neurodevelopmental disorder. The first-line therapeutic for
ADHD, methylphenidate, can cause serious side effects including weight loss, insomnia …

Trans-synaptic regulation of metabotropic glutamate receptors by Elfn proteins in health and disease

H Matsunaga, J Aruga - Frontiers in Neural Circuits, 2021 - frontiersin.org
Trans-regulation of G protein-coupled receptors (GPCRs) by leucine-rich repeat (LRR)
transmembrane proteins has emerged as a novel type of synaptic molecular interaction in …