Dendritic integration: 60 years of progress

GJ Stuart, N Spruston - Nature neuroscience, 2015 - nature.com
Understanding how individual neurons integrate the thousands of synaptic inputs they
receive is critical to understanding how the brain works. Modeling studies in silico and …

A cellular mechanism for cortical associations: an organizing principle for the cerebral cortex

M Larkum - Trends in neurosciences, 2013 - cell.com
A basic feature of intelligent systems such as the cerebral cortex is the ability to freely
associate aspects of perceived experience with an internal representation of the world and …

The variable discharge of cortical neurons: implications for connectivity, computation, and information coding

MN Shadlen, WT Newsome - Journal of neuroscience, 1998 - Soc Neuroscience
Cortical neurons exhibit tremendous variability in the number and temporal distribution of
spikes in their discharge patterns. Furthermore, this variability appears to be conserved over …

Pyramidal neurons: dendritic structure and synaptic integration

N Spruston - Nature Reviews Neuroscience, 2008 - nature.com
Pyramidal neurons are characterized by their distinct apical and basal dendritic trees and
the pyramidal shape of their soma. They are found in several regions of the CNS and …

Noise, neural codes and cortical organization

MN Shadlen, WT Newsome - Current opinion in neurobiology, 1994 - Elsevier
Cortical circuitry must facilitate information transfer in accordance with a neural code. In this
article we examine two candidate neural codes: information is represented in the spike rate …

Active propagation of somatic action potentials into neocortical pyramidal cell dendrites

GJ Stuart, B Sakmann - Nature, 1994 - nature.com
THE dendrites of neurons in the mammalian central nervous system have been considered
as electrically passive structures which funnel synaptic potentials to the soma and axon …

[图书][B] Computational Explorations in Cognitive Neuroscience: Understanding the Mind by Simulating the Brain

R O'Reilly - 2000 - books.google.com
This text, based on a course taught by Randall O'Reilly and Yuko Munakata over the past
several years, provides an in-depth introduction to the main ideas in the computational …

Pyramidal neuron as two-layer neural network

P Poirazi, T Brannon, BW Mel - Neuron, 2003 - cell.com
The pyramidal neuron is the principal cell type in the mammalian forebrain, but its function
remains poorly understood. Using a detailed compartmental model of a hippocampal CA1 …

Active properties of neocortical pyramidal neuron dendrites

G Major, ME Larkum, J Schiller - Annual review of neuroscience, 2013 - annualreviews.org
Dendrites are the main recipients of synaptic inputs and are important sites that determine
neurons' input-output functions. This review focuses on thin neocortical dendrites, which …

Dendritic excitability and synaptic plasticity

PJ Sjostrom, EA Rancz, A Roth… - Physiological …, 2008 - journals.physiology.org
Most synaptic inputs are made onto the dendritic tree. Recent work has shown that dendrites
play an active role in transforming synaptic input into neuronal output and in defining the …