Cancer-associated cachexia—understanding the tumour macroenvironment and microenvironment to improve management

JM Argilés, FJ López-Soriano, B Stemmler… - Nature Reviews …, 2023 - nature.com
Cachexia is a devastating, multifactorial and often irreversible systemic syndrome
characterized by substantial weight loss (mainly of skeletal muscle and adipose tissue) that …

The burden of cancer, government strategic policies, and challenges in Pakistan: A comprehensive review

A Ali, MF Manzoor, N Ahmad, RM Aadil, H Qin… - Frontiers in …, 2022 - frontiersin.org
Cancer is a severe condition characterized by uncontrolled cell division and increasing
reported mortality and diagnostic cases. In 2040, an estimated 28.4 million cancer cases are …

Current therapeutic targets in cancer cachexia: a pathophysiologic approach

KC Kadakia, JM Hamilton-Reeves… - American Society of …, 2023 - ascopubs.org
Significant progress in our understanding of cancer cachexia has occurred in recent years.
Despite these advances, no pharmacologic agent has achieved US Food and Drug …

Perioperative nutrition management for gastric cancer

R Xu, XD Chen, Z Ding - Nutrition, 2022 - Elsevier
Gastric cancer is one of the most frequently diagnosed and the leading cause of cancer
death worldwide. Malnutrition is a substantial problem in patients with gastric cancer …

Prognostic value of geriatric nutritional risk index for patients with non-small cell lung cancer: a systematic review and meta-analysis

F Shen, Y Ma, W Guo, F Li - Lung, 2022 - Springer
Objective The purpose of this review was to collate evidence on the prognostic ability of the
geriatric nutritional risk index (GNRI) for predicting overall survival (OS) and disease-free …

Impact of perioperative immunonutrition on postoperative outcomes for patients undergoing head and neck or gastrointestinal cancer surgeries: a systematic review …

R Matsui, M Sagawa, A Sano, M Sakai… - Annals of …, 2024 - journals.lww.com
Objective: To clarify whether perioperative immunonutrition is effective in adult patients with
or without malnutrition undergoing elective surgery for head and neck (HAN) or …

Diet, nutrient supply, and tumor immune responses

CL McIntyre, A Temesgen, L Lynch - Trends in Cancer, 2023 - cell.com
Nutrients are essential for cell function. Immune cells operating in the complex tumor
microenvironment (TME), which has a unique nutrient composition, face challenges of …

Exosomal IL-8 derived from Lung Cancer and Colon Cancer cells induced adipocyte atrophy via NF-κB signaling pathway

H Xiong, J Ye, K Xie, W Hu, N Xu, H Yang - Lipids in Health and Disease, 2022 - Springer
Background Cytokines secreted in the tumor microenvironment function in cancer cachexia
(CC), a common clinicopathological syndrome associated with adipocyte wasting and …

Multimodal prerehabilitation for elderly patients with sarcopenia in colorectal surgery

J Wu, H Chi, S Kok, JMW Chua… - Annals of …, 2023 - pmc.ncbi.nlm.nih.gov
Sarcopenia, which is characterized by progressive and generalized loss of skeletal muscle
mass and strength, has been well described to be associated with numerous poor …

Narrative review: nutritional strategies for ageing populations-focusing on dysphagia and geriatric nutritional needs

E Cava, M Lombardo - European Journal of Clinical Nutrition, 2024 - nature.com
The increase in elderly populations worldwide highlights the urgency of addressing age-
related problems through effective nutritional management to enhance the well-being of the …