Cerium belongs to the family of the lanthanides, which constitute (together with scandium
and yttrium) the so-called rare earth elements. Cerium is the most abundant of these …

Quinazolinone and its congeners are ubiquitous structural motifs found in numerous natural
products due to their wide applications as anticancer, antiviral, anti-inflammatory, antifolate …

DNA topoisomerases comprise a major aspect of basic cellular biology and are molecular
targets for a variety of drugs like antibiotics, antibacterials and anticancer drugs. They act by …

Covering: 2006 to 2018 The application of the 6π-azaelectrocyclization of azatrienes as a
key strategy for the synthesis of natural products, their analogs and related bioactive or …

Luotonins are alkaloids from the aerial parts of Peganum nigellastrum Bunge. that display
three major skeleton types. Luotonins A, B, and E are pyrroloquinazolino-quinoline …

Luotonin A (L), a novel natural cytotoxic and anti-inflammatory alkaloid, chelated with copper
(II) to improve its cytotoxic effect against the cancer cells. The complexes [Cu (L) H 2 OCl] Cl …

Topoisomerases are DNA processing enzymes that relieve supercoiling (torsional strain) in
DNA, are necessary for normal cellular division, and act by nicking (and then religating) …

Starting with inexpensive reagents, a self-directed chemical process with the aid of a single
metal triflate was readily achieved to concomitantly construct quinazoline and …

A microwave-assisted method for the palladium-catalyzed direct arylation of quinazolin-4-
one has been developed under copper-assistance. This method is applicable to a wide …

Fig. 1. Simple Alkaloids Derived from 4 (3H)-Quinazolinone Chart 1 present method is
applicable to compounds with an OH group. Although the compound with an OH group, 2 …