Inspired by molecular motors in biology, there has been significant progress in building
artificial molecular motors, using a number of quite distinct approaches. As the constructs …

Inspired by biology, great progress has been made in creating artificial molecular motors.
However, the dream of harnessing proteins–the building blocks selected by nature–to …

Simulations can help unravel the complicated ways in which molecular structure determines
function. Here, we use molecular simulations to show how slight alterations of a molecular …

Particles with ligand–receptor contacts bind and unbind fluctuating “legs” to surfaces, whose
fluctuations cause the particle to diffuse. Quantifying the diffusion of such “nanoscale …

Transient bonds between fast linkers and slower particles are widespread in physical and
biological systems. Despite their diverse structure and function, a commonality is that the …

Despite a relatively low mutation rate, the large number of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infections has allowed for substantial genetic …

Thermodynamic uncertainty relations (TURs) relate precision to the dissipation rate, yet the
inequalities can be far from saturation. Indeed, in catenane molecular motor simulations, we …

Influenza A virus (IAV) infection relies on the action of the hemagglutinin (HA) and
neuraminidase (NA) membrane proteins. The HA ligands anchor the IAV virion to the cell's …

A quantitative model of the mobility of ligand-presenting particles at the interface is pivotal to
understanding important systems in biology and nanotechnology. In this work, we …

Nano-and micro-scale burnt bridge ratchet motors, which translocate via “guide” molecules
that bind to and degrade a field of “fuel” molecules, have recently emerged in several …