Vitamin C and the lens: new insights into delaying the onset of cataract

JC Lim, M Caballero Arredondo, AJ Braakhuis… - Nutrients, 2020 - mdpi.com
Cataracts or clouding of the lens is the leading cause of blindness in the world. Age and
diabetes are major risk factors, and with an increasing aging and diabetic population, the …

Vitreous substitutes: a comprehensive review

TT Kleinberg, RT Tzekov, L Stein, N Ravi… - Survey of …, 2011 - Elsevier
Vitreoretinal disorders constitute a significant portion of treatable ocular disease. Advances
in vitreoretinal surgery have included the development and characterization of suitable …

Physiology of vitreous surgery

E Stefánsson - Graefe's archive for clinical and experimental …, 2009 - Springer
Vitreous surgery has various physiological and clinical consequences, both beneficial and
harmful. Vitrectomy reduces the risk of retinal neovascularization, while increasing the risk of …

Lens gap junctions in growth, differentiation, and homeostasis

RT Mathias, TW White, X Gong - Physiological reviews, 2010 - journals.physiology.org
The cells of most mammalian organs are connected by groups of cell-to-cell channels called
gap junctions. Gap junction channels are made from the connexin (Cx) family of proteins …

Safe, Durable, and Sustainable Self-Powered Smart Contact Lenses

D Kang, JI Lee, B Maeng, S Lee, Y Kwon, MS Kang… - ACS …, 2022 - ACS Publications
Smart contact lenses have the potential to serve as noninvasive healthcare devices or virtual
displays. However, their implementation is limited by the lack of suitable power sources for …

Nrf2 as a target for prevention of age‐related and diabetic cataracts by against oxidative stress

XF Liu, JL Hao, T Xie, TH Malik, CB Lu, C Liu… - Aging cell, 2017 - Wiley Online Library
Cataract is one of the most important causes of blindness worldwide, with age‐related
cataract being the most common one. Agents preventing cataract formation are urgently …

Etiology of posterior subcapsular cataracts based on a review of risk factors including aging, diabetes, and ionizing radiation

RB Richardson, EA Ainsbury, CR Prescott… - International journal of …, 2020 - Taylor & Francis
Purpose Since the exact development of posterior subcapsular cataracts (PSCs) is poorly
understood, we review various risk factors and propose a two-stage etiology for PSCs …

Hallmarks of lens aging and cataractogenesis

TFL Wishart, M Flokis, DY Shu, SJ Das… - Experimental Eye …, 2021 - Elsevier
Lens homeostasis and transparency are dependent on the function and intercellular
communication of its epithelia. While the lens epithelium is uniquely equipped with …

A contemporary concept of the blood–aqueous barrier

TF Freddo - Progress in retinal and eye research, 2013 - Elsevier
This review traces the evolution of the concept of the blood–aqueous barrier (BAB) during
the past 20 years. The Classical model simply stipulated that the tight junctions of the iris …

Maintaining transparency: a review of the developmental physiology and pathophysiology of two avascular tissues

DC Beebe - Seminars in cell & developmental biology, 2008 - Elsevier
The lens and cornea are transparent and usually avascular. Controlling nutrient supply
while maintaining transparency is a physiological challenge for both tissues. During sleep …