Kawasaki disease: etiopathogenesis and novel treatment strategies

S Agarwal, DK Agrawal - Expert review of clinical immunology, 2017 - Taylor & Francis
Introduction: Kawasaki disease is an acute febrile systemic vasculitis that predominantly
occurs in children below five years of age. Its etiopathogenesis is still not clear, but it is …

Multisystem inflammatory syndrome and autoimmune diseases following COVID-19: molecular mechanisms and therapeutic opportunities

P Hosseini, MS Fallahi, G Erabi, M Pakdin… - Frontiers in molecular …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome-
coronavirus 2 (SARS-CoV-2), has led to huge concern worldwide. Some SARS-CoV-2 …

[HTML][HTML] Preventing coronary artery lesions in Kawasaki disease

HC Kuo - Biomedical journal, 2017 - Elsevier
A form of systemic vasculitis that affects mostly small and medium-sized vessels, Kawasaki
disease (KD) is most commonly found in children under the age of 5 years old. Though its …

The roles of genetic factors in Kawasaki disease: a systematic review and meta-analysis of genetic association studies

X Xie, X Shi, M Liu - Pediatric Cardiology, 2018 - Springer
This systematic review and meta-analysis aimed to better elucidate the roles of genetic
factors in Kawasaki disease (KD), and determine the potential genetic biomarkers of KD …

Prediction for intravenous immunoglobulin resistance by using weighted genetic risk score identified from genome-wide association study in Kawasaki disease

HC Kuo, HSC Wong, WP Chang, BK Chen… - Circulation …, 2017 - Am Heart Assoc
Background—Intravenous immunoglobulin (IVIG) is the treatment of choice in Kawasaki
disease (KD). IVIG is used to prevent cardiovascular complications related to KD. However …

Red blood cell distribution width and tumor necrosis factor-α for the early prediction of coronary artery lesion in Kawasaki disease: a retrospective study

J Li, D Li, M Hu, H Huang, S Xu, H Li - European journal of pediatrics, 2022 - Springer
We aimed to identify novel risk factors for the early prediction of coronary artery lesion (CAL)
in children with Kawasaki disease (KD). We retrospectively analyzed data from hospitalized …

Intravenous immunoglobulin skews macrophages to an anti-inflammatory, IL-10-producing activation state

LK Kozicky, ZY Zhao, SC Menzies… - Journal of Leucocyte …, 2015 - academic.oup.com
Intravenous Ig is used to treat autoimmune or autoinflammatory disorders, but the
mechanism by which it exerts its immunosuppressive activity is not understood completely …

Chemical and biochemical aspects of molecular hydrogen in treating Kawasaki Disease and COVID-19

KD Chen, WC Lin, HC Kuo - Chemical Research in Toxicology, 2021 - ACS Publications
Kawasaki disease (KD) is a systemic vasculitis and is the most commonly acquired heart
disease among children in many countries, which was first reported 50 years ago in Japan …

Interferon-gamma genetic polymorphism and expression in Kawasaki disease

YH Huang, YW Hsu, HF Lu, HSC Wong, HR Yu… - Medicine, 2016 - journals.lww.com
Kawasaki disease (KD) is a systemic vasculitis of unknown etiology. IFNG gene encoding
interferon (IFN)-γ, produced by natural killer cells and T cells, has been suggested to play an …

[HTML][HTML] Identifying genetic hypomethylation and upregulation of toll-like receptors in Kawasaki disease

YH Huang, SC Li, LH Huang, PC Chen, YY Lin… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Kawasaki disease (KD) is an acute febrile systemic vasculitis that occurs in children and is
characterized by elevated levels of proinflammatory cytokines. Toll-like receptors (TLRs) …