Oncolytic viruses (OVs) target and destroy cancer cells while sparing their normal
counterparts. These viruses have been evaluated in numerous studies at both pre-clinical …

Oncolytic herpes simplex virus (oHSV) was one of the first genetically-engineered oncolytic
viruses. Because HSV is a natural human pathogen that can cause serious disease, it is …

Equine Herpesvirus‐1 infection has been assessed according to the criteria of the Animal
Health Law (AHL), in particular criteria of: Article 7 on disease profile and impacts, Article 5 …

ABSTRACT Caprine Herpesvirus type 1 (CpHV-1) is a species-specific herpes virus able to
induce apoptosis in several biological systems. In the present study we aimed to investigate …

Programed cell death is an antiviral mechanism by which the host limits viral replication and
protects uninfected cells. Many viruses encode proteins resistant to programed cell death to …

Oncolytic viruses have the ability to infect tumor cells and leave healthy cells intact. In this
study, bovine herpesvirus 1 (BHV1; Los Angeles, Cooper, and SV56/90 strains) and bovine …

Equid alphaherpesvirus 1 (EHV-1) causes respiratory diseases, abortion, and neurological
disorders in horses. Recently, the oncolytic potential of this virus and its possible use in …

Histone deacetylase (HDAC) inhibitors represent a promising new therapy against
malignant glioma. When used in conjunction with oncolytic viral vectors, these compounds …

In recent years there have been a growing number of reports on applying viruses in
oncological treatment. In the present study, we demonstrated for the first time that animal …

Cancer is one of the most frequent causes of death in Poland and in the world. The low
efficacy of conventional treatment, as well as the high toxicity of the usual therapies, have …