Nitric oxide and major depression
A Dhir, SK Kulkarni - Nitric oxide, 2011 - Elsevier
Nitric oxide has been known to play a significant role in the pathophysiology of various
disorders of the body. Despite its very short half-life, nitric oxide is known to modulate …
disorders of the body. Despite its very short half-life, nitric oxide is known to modulate …
[HTML][HTML] Neuronal nitric oxide synthase and affective disorders
QG Zhou, XH Zhu, AD Nemes, DY Zhu - IBRO reports, 2018 - Elsevier
Affective disorders including major depressive disorder (MDD), bipolar disorder (BPD), and
general anxiety affect more than 10% of population in the world. Notably, neuronal nitric …
general anxiety affect more than 10% of population in the world. Notably, neuronal nitric …
Hesperidin exerts antidepressant-like effects in acute and chronic treatments in mice: possible role of l-arginine-NO-cGMP pathway and BDNF levels
F Donato, MG de Gomes, ATR Goes… - Brain research …, 2014 - Elsevier
Abstract Hesperidin (4′-methoxy-7-O-rutinosyl-3′, 5-dihydroxyflavanone), a naturally
occurring flavanone glycoside, was previously shown to produce an antidepressant-like …
occurring flavanone glycoside, was previously shown to produce an antidepressant-like …
Thermoreversible Nasal In situ Gel of Venlafaxine Hydrochloride: Formulation, Characterization, and Pharmacodynamic Evaluation
MJ Bhandwalkar, AM Avachat - Aaps Pharmscitech, 2013 - Springer
In order to improve the bioavailability of the antidepressant drug, venlafaxine hydrochloride,
in situ mucoadhesive thermoreversible gel, was formulated using Lutrol F127 (18%) as a …
in situ mucoadhesive thermoreversible gel, was formulated using Lutrol F127 (18%) as a …
Prevention of chronic stress-induced depression-like behavior by inducible nitric oxide inhibitor
D Wang, SC An, X Zhang - Neuroscience letters, 2008 - Elsevier
Depression is associated with significant morbidity and functional disability, and it is thus
important to reveal the mechanism of depression. A variety of studies suggest an …
important to reveal the mechanism of depression. A variety of studies suggest an …
Antidepressant-like effect of nitric oxide synthase inhibitors and sildenafil against lipopolysaccharide-induced depressive-like behavior in mice
VS Tomaz, RC Cordeiro, AMN Costa, DF De Lucena… - Neuroscience, 2014 - Elsevier
Inflammation, oxidative and nitrosative stress underlie depression being assessed in
rodents by the systemic administration of lipopolysacharide (LPS). There is an increasing …
rodents by the systemic administration of lipopolysacharide (LPS). There is an increasing …
Involvement of nitric oxide (NO) signaling pathway in the antidepressant action of bupropion, a dopamine reuptake inhibitor
A Dhir, SK Kulkarni - European journal of pharmacology, 2007 - Elsevier
The present study was undertaken to elucidate the alterations in various behavioral and
neurochemical basis of antidepressant action of bupropion [(±)-α-t-butylamino-3 …
neurochemical basis of antidepressant action of bupropion [(±)-α-t-butylamino-3 …
Antidepressant-like effect of pioglitazone in the forced swimming test in mice: the role of PPAR-gamma receptor and nitric oxide pathway
MS Sadaghiani, M Javadi-Paydar… - Behavioural brain …, 2011 - Elsevier
In this study, the potential antidepressant-like effects of pioglitazone and the possible
involvement of peroxisome proliferator-activated receptor gamma (PPARγ) and nitric oxide …
involvement of peroxisome proliferator-activated receptor gamma (PPARγ) and nitric oxide …
Effect of various classes of antidepressants in behavioral paradigms of despair
SK Kulkarni, A Dhir - Progress in Neuro-Psychopharmacology and …, 2007 - Elsevier
The forced swim test (FST) and tail suspension test (TST) are widely used as animal models
for screening potential antidepressants. Immobility or despair behavior produced in both …
for screening potential antidepressants. Immobility or despair behavior produced in both …
Venlafaxine protects against stress-induced oxidative DNA damage in hippocampus during antidepressant testing in mice
BA Abdel-Wahab, RH Salama - Pharmacology Biochemistry and Behavior, 2011 - Elsevier
Venlafaxine (VLF) is an approved antidepressant that is claimed to have superior clinical
efficacy to comparable drugs. Recently, many studies showed the relationship between …
efficacy to comparable drugs. Recently, many studies showed the relationship between …