Exosomal circRNA serves a novel genetic information molecule, facilitating communication
between tumor cells and microenvironmental cells, such as immune cells, fibroblasts, and …

Early cancer diagnosis considerably reduces mortality rates, leading to improved patient
outcomes and ultimately saving lives. As such, the urgency of developing efficient methods …

Electrochemical nucleic acid biosensor has demonstrated great promise in clinical
diagnostic tests, mainly because of its flexibility, high efficiency, low cost, and easy …

Chemotherapy resistance typically leads to tumour recurrence and is a major obstacle to
cancer treatment. Increasing numbers of circular RNAs (circRNAs) have been confirmed to …

The combination of CRISPR technology and electrochemical sensors has sparked a
paradigm shift in the landscape of point-of-care (POC) diagnostics. This review explores the …

Herein, we report a carbon-stabilized porous silicon (pSi)-based electrochemical biosensing
platform for the label-and amplification-free detection of bacterial 16S rRNA gene fragments …

Innovative signal amplification and transduction play pivotal roles in bioanalysis. Herein,
cascading CRISPR/Cas and the nanozyme are integrated with electronic amplification in an …

The clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-
associated (Cas) proteins are adaptive immune system found in bacteria and archaea. This …

The accelerated evolution of Clustered Regularly Interspaced Short Palindromic Repeats
(CRISPR) technology has facilitated the development of a versatile and user-friendly …

Depression is one of the most common mental disorders and is mainly characterized by low
mood or lack of interest and pleasure. It can be accompanied by varying degrees of …