Anti-Alzheimer activity of new coumarin-based derivatives targeting acetylcholinesterase inhibition

NN Kamel, HF Aly, GI Fouad, SS Abd El-Karim… - RSC …, 2023 - pubs.rsc.org
New 2-oxo-chromene-7-oxymethylene acetohydrazide derivatives 4a–d were designed and
synthesized with a variety of bioactive chemical fragments. The newly synthesized …

Scabicidal potential of coconut seed extract in rabbits via downregulating inflammatory/immune cross talk: A comprehensive phytochemical/GC-MS and in silico proof

EM Zahran, NMR Abdel-Maqsoud, OY Tammam… - Antibiotics, 2022 - mdpi.com
Scabies is an invasive skin condition caused by Sarcoptes scabiei mites. The present study
investigates the antiscabies potential of coconut seed extract (CSE) in rabbits. GC-MS …

Comparative Metabolic Study of Tamarindus indica L.'s Various Organs Based on GC/MS Analysis, In Silico and In Vitro Anti-Inflammatory and Wound Healing …

SH Aly, MA El-Hassab, SS Elhady, HA Gad - Plants, 2022 - mdpi.com
The chemical composition of the n-hexane extract of Tamarindus indica's various organs—
bark, leaves, seeds, and fruits (TIB, TIL, TIS, TIF)—was investigated using gas …

New Halogenated Compounds from Halimeda macroloba Seaweed with Potential Inhibitory Activity against Malaria

AH Elmaidomy, EM Zahran, R Soltane, A Alasiri… - Molecules, 2022 - mdpi.com
Malaria is one of the most important infectious diseases worldwide. The causative of the
most severe forms of malaria, Plasmodium falciparum, has developed resistances against …

Vitis vinifera leaf extract liposomal Carbopol gel preparation's potential wound healing and antibacterial benefits: in vivo, phytochemical, and computational …

AH Elmaidomy, SA Mohamad, M Abdelnaser… - Food & Function, 2023 - pubs.rsc.org
Vitis vinifera Egyptian edible leaf extract loaded on a soybean lecithin, cholesterol, and
Carbopol gel preparation (VVL-liposomal gel) was prepared to maximize the in vivo wound …

Para-Substituted Thiosemicarbazones as Cholinesterase Inhibitors: Synthesis, In Vitro Biological Evaluation, and In Silico Study

M Khan, H Gohar, A Alam, A Wadood, A Shareef… - ACS …, 2023 - ACS Publications
The current research reports the synthesis of 14 para-substituted thiosemicarbazone
derivatives in good to excellent yields using standard procedures. Initially, 4 …

The Wound-Healing Potential of Olea europaea L. Cv. Arbequina Leaves Extract: An Integrated In Vitro, In Silico, and In Vivo Investigation

T Al-Warhi, AH Elmaidomy, SA Maher, DH Abu-Baih… - Metabolites, 2022 - mdpi.com
Olea europaea L. Cv. Arbequina (OEA)(Oleaceae) is an olive variety species that has
received little attention. Besides our previous work for the chemical profiling of OEA leaves …

New cytotoxic dammarane type saponins from Ziziphus spina-christi

AH Elmaidomy, A El Zawily, AK Salem, FH Altemani… - Scientific reports, 2023 - nature.com
Cancer is the world's second-leading cause of death. Drug development efforts frequently
focus on medicinal plants since they are a valuable source of anticancer medications. A …

The Protective and Therapeutic Anti-Alzheimer Potential of Olea europaea L. cv. Picual: An In Silico and In Vivo Study

AA Bagalagel, SS El-Hawary, R Alaaeldin… - Metabolites, 2022 - mdpi.com
LC-HRESIMS metabolomic profiling of Olea europaea L. cv. Picual (OEP)(Saudi Arabian
olive cultivar, F. Oleacea) revealed 18 compounds. Using pharmacology networking to …

Role of Tamarindus indica L. in diabetes: A systematic review of current evidence

INM Adnan, JJ Jayapalan, SM Junit, AA Aziz - South African Journal of …, 2025 - Elsevier
Background Diabetes mellitus (DM) is a major non-communicable disease that impacts
populations globally, resulting in over 6 million deaths in 2021 alone. Patients with DM often …