Ivermectin is one of the most important drugs in veterinary and human medicine for the
control of parasitic infection and was the joint focus of the 2015 Nobel Prize in Physiology or …

Dirofilaria immitis, also known as heartworm, is a major parasitic threat for dogs and cats
around the world. Because of its impact on the health and welfare of companion animals …

Mass drug administration (MDA) is a means of delivering safe and inexpensive essential
medicines based on the principles of preventive chemotherapy, where populations or sub …

The avermectins and milbemycins contain a common macrocyclic lactone (ML) ring, but are
fermentation products of different organisms. The principal structural difference is that …

Macrocyclic lactone (ML) anthelmintics are the most important class of anthelmintics
because of our high dependence on them for the control of nematode parasites and some …

Background The morbidity and socioeconomic effects of onchocerciasis, a parasitic disease
that is primarily endemic in sub-Saharan Africa, have motivated large morbidity and …

Control of helminth parasites is a key challenge for human and veterinary medicine. In the
absence of effective vaccines and adequate sanitation, prophylaxis and treatment commonly …

Anthelmintic resistance is a significant threat to livestock production systems worldwide and
is emerging as an important issue in companion animal parasite management. It is also an …

Anthelmintic resistance has a great impact on livestock production systems worldwide, is an
emerging concern in companion animal medicine, and represents a threat to our ongoing …

Heartworm disease, caused by Dirofilaria immitis, can be lethal in dogs and cats. It is
transmitted by mosquitoes, and occurs in many parts of the world. Prevention relies on …