[HTML][HTML] Chagas disease: review of needs, neglect, and obstacles to treatment access in Latin America

E Pinheiro, L Brum-Soares, R Reis… - Revista da sociedade …, 2017 - SciELO Brasil
After more than one century since its discovery, Chagas disease is still extremely prevalent
in 21 Latin American countries. Chagas disease is one of the most concerning public health …

Clinical trials for Chagas disease: etiological and pathophysiological treatment

BMS Gonzaga, RR Ferreira, LL Coelho… - Frontiers in …, 2023 - frontiersin.org
Chagas disease (CD) is caused by the flagellate protozoan Trypanosoma cruzi. It is
endemic in Latin America. Nowadays around 6 million people are affected worldwide, and …

3ª diretriz brasileira de transplante cardíaco

F Bacal, FG Marcondes-Braga, LEP Rohde… - Arquivos brasileiros de …, 2018 - SciELO Brasil
Prezados colegas, Grandes avanços no diagnóstico, monitorização e tratamento da
Insuficiência Cardíaca (IC) foram observados nos últimos anos, com impactos reais na …

Beneficial effects of benznidazole in Chagas disease: NIH SaMi-Trop cohort study

CS Cardoso, ALP Ribeiro, CDL Oliveira… - PLoS neglected …, 2018 - journals.plos.org
Background The effectiveness of anti-parasite treatment with benznidazole in the chronic
Chagas disease (ChD) remains uncertain. We evaluated, using data from the NIH …

The repositioned drugs disulfiram/diethyldithiocarbamate combined to benznidazole: Searching for Chagas disease selective therapy, preventing toxicity and drug …

J Almeida-Silva, DS Menezes… - Frontiers in Cellular …, 2022 - frontiersin.org
Chagas disease (CD) affects at least 6 million people in 21 South American countries
besides several thousand in other nations all over the world. It is estimated that at least …

Therapeutic miR-21 silencing reduces cardiac fibrosis and modulates inflammatory response in chronic chagas disease

CKV Nonaka, GL Sampaio… - International Journal of …, 2021 - mdpi.com
Chagas disease, caused by the parasite Trypanosoma cruzi (T. cruzi), remains a serious
public health problem for which there is no effective treatment in the chronic stage. Intense …

Exploring the parasite load and molecular diversity of Trypanosoma cruzi in patients with chronic Chagas disease from different regions of Brazil

I Rodrigues-dos-Santos, MF Melo… - PLoS neglected …, 2018 - journals.plos.org
Chagas disease is still a major public health issue in many Latin American countries. One of
the current major challenges is to find an association between Trypanosoma cruzi discrete …

[HTML][HTML] How universal is coverage and access to diagnosis and treatment for Chagas disease in Colombia? A health systems analysis

ZM Cucunubá, JM Manne-Goehler, D Díaz… - Social Science & …, 2017 - Elsevier
Limited access to Chagas disease diagnosis and treatment is a major obstacle to reaching
the 2020 World Health Organization milestones of delivering care to all infected and ill …

[HTML][HTML] Acute Chagas disease in the state of Pará, Amazon Region: is it increasing?

VRC Santos, J Meis, W Savino, JAA Andrade… - Memórias do Instituto …, 2018 - SciELO Brasil
Acute Chagas disease (ACD) has a distinct epidemiological profile in the Amazon Region,
with cases and outbreaks of Trypanosoma cruzi infection being possibly related to the …

Mortalidade por doenças tropicais negligenciadas no Piauí, Nordeste do Brasil: tendência temporal e padrões espaciais, 2001-2018

SPS Brito, AF Ferreira, MS Lima… - Epidemiologia e Serviços …, 2022 - SciELO Brasil
Objetivo Analisar tendência temporal e padrões espaciais da mortalidade por doenças
tropicais negligenciadas (DTNs) no Piauí, Brasil, 2001-2018. Métodos Estudo ecológico …