PURPOSE Accurate genotyping of individuals with inherited retinal diseases (IRD) is
essential for patient management and identifying suitable candidates for gene therapies …

Genetic medicine is offering hope as new therapies are emerging for many previously
untreatable diseases. The eye is at the forefront of these advances, as exemplified by the …

Background Emerging treatments are being developed for inherited retinal diseases,
requiring a clear understanding of natural progression and a database of potential …

Many gene therapies are in development for treating people with inherited retinal diseases
(IRD). We hypothesized that potential recipients of gene therapy would have knowledge …

Gene therapies, despite of being a relatively new therapeutic approach, have a potential to
become an important alternative to current treatment strategies in glaucoma. Since …

With advances in gene‐based therapies for heritable retinal diseases, primary eye care
clinicians should be informed on ocular genetics topics. This cross‐sectional survey …

Purpose: This systematic review evaluates the safety and efficacy of ocular gene therapy
using adeno-associated virus (AAV). Methods: MEDLINE, Embase, Cochrane Central …

Adaptive optics (AO) imaging enables direct, objective assessments of retinal cells.
Applications of AO show great promise in advancing our understanding of the etiology of …

Aim: This study aimed to develop phosphatase-responsive ζ potential converting
nanocarriers utilizing polyphosphate-coated cell-penetrating peptide (CPP)-decorated …

Age-related macular degeneration (AMD) is a progressive neurodegenerative disease that
is the world's leading cause of blindness in the aging population. Although the clinical …