HIV infection and coronary heart disease: mechanisms and management

PY Hsue, DD Waters - Nature Reviews Cardiology, 2019 - nature.com
Antiretroviral therapy has largely transformed HIV infection into a chronic disease condition.
As such, physicians and other providers caring for individuals living with HIV infection need …

Metabolic complications affecting adipose tissue, lipid and glucose metabolism associated with HIV antiretroviral treatment

C Lagathu, V Béréziat, J Gorwood… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Efficient antiretroviral-treatment (ART) generally allows control of HIV infection.
However, persons-living-with-HIV (PLWH), when aging, present a high prevalence of …

Doravirine versus ritonavir-boosted darunavir in antiretroviral-naive adults with HIV-1 (DRIVE-FORWARD): 48-week results of a randomised, double-blind, phase 3 …

JM Molina, K Squires, PE Sax, P Cahn, J Lombaard… - The lancet HIV, 2018 - thelancet.com
Background Doravirine is a novel non-nucleoside reverse transcriptase inhibitor (NNRTI)
with a pharmacokinetic profile supporting once-daily dosing, and potent in-vitro activity …

Rilpivirine attenuates liver fibrosis through selective STAT1-mediated apoptosis in hepatic stellate cells

A Martí-Rodrigo, F Alegre, ÁB Moragrega… - Gut, 2020 - gut.bmj.com
Objective Liver fibrosis constitutes a major health problem worldwide due to its rapidly
increasing prevalence and the lack of specific and effective treatments. Growing evidence …

[HTML][HTML] Impact of antiretroviral therapy on lipid metabolism of human immunodeficiency virus-infected patients: Old and new drugs

J da Cunha, LMF Maselli, ACB Stern… - World journal of …, 2015 - ncbi.nlm.nih.gov
For human immunodeficiency virus (HIV)-infected patients, the 1990s were marked by the
introduction of highly active antiretroviral therapy (HAART) representing a new perspective …

A review of non-alcoholic fatty liver disease in HIV-infected patients: the next big thing?

BJ van Welzen, T Mudrikova, A El Idrissi… - Infectious diseases and …, 2019 - Springer
The burden of liver-related morbidity remains high among HIV-infected patients, despite
advances in the treatment of HIV and viral hepatitis. Especially, the impact of non-alcoholic …

Incidence of hypertension in people with HIV who are treated with integrase inhibitors versus other antiretroviral regimens in the RESPOND cohort consortium

DM Byonanebye, MN Polizzotto, B Neesgaard… - HIV …, 2022 - Wiley Online Library
Objective To compare the incidence of hypertension in people living with HIV receiving
integrase strand transfer inhibitor (INSTI)‐based antiretroviral therapy (ART) versus non …

NNRTI and liver damage: evidence of their association and the mechanisms involved

AM Benedicto, I Fuster-Martínez, J Tosca… - Cells, 2021 - mdpi.com
Due to the improved effectiveness and safety of combined antiretroviral therapy, human
immunodeficiency virus (HIV) infection has become a manageable, chronic condition rather …

Combination of metformin/efavirenz/fluoxetine exhibits profound anticancer activity via a cancer cell-specific ROS amplification

BG Kang, M Shende, G Inci, SH Park… - Cancer Biology & …, 2023 - Taylor & Francis
The possible anticancer activity of combination (M+ E+ F) of metformin (M), efavirenz (E),
and fluoxetine (F) was investigated in normal HDF cells and HCT116 human colon cancer …

Cardiovascular disease and risk assessment in people living with HIV: Current practices and novel perspectives

PC Fragkou, CD Moschopoulos, D Dimopoulou… - Hellenic Journal of …, 2023 - Elsevier
Human immunodeficiency virus (HIV) infection represents a major cardiovascular risk factor,
and the cumulative cardiovascular disease (CVD) burden among aging people living with …