Endocrine disrupting chemicals: exposure, effects on human health, mechanism of action, models for testing and strategies for prevention

B Yilmaz, H Terekeci, S Sandal… - Reviews in endocrine and …, 2020 - Springer
Abstract Endocrine Disrupting Chemicals (EDCs) are a global problem for environmental
and human health. They are defined as “an exogenous chemical, or mixture of chemicals …

Physical activity, cardiorespiratory fitness, and the metabolic syndrome

J Myers, P Kokkinos, E Nyelin - Nutrients, 2019 - mdpi.com
Both observational and interventional studies suggest an important role for physical activity
and higher fitness in mitigating the metabolic syndrome. Each component of the metabolic …

Genetics of human primary hypertension: focus on hormonal mechanisms

W Manosroi, GH Williams - Endocrine reviews, 2019 - academic.oup.com
Increasingly, primary hypertension is being considered a syndrome and not a disease, with
the individual causes (diseases) having a common sign—an elevated blood pressure. To …

Role of Caveolin‐1 in diabetes and its complications

D Haddad, A Al Madhoun, R Nizam… - … medicine and cellular …, 2020 - Wiley Online Library
It is estimated that in 2017 there were 451 million people with diabetes worldwide. These
figures are expected to increase to 693 million by 2045; thus, innovative preventative …

Obesogenic endocrine disruptors and obesity: myths and truths

G Muscogiuri, L Barrea, D Laudisio, S Savastano… - Archives of …, 2017 - Springer
Obesogenic endocrine disruptors, also known as obesogens, are chemicals potentially
involved in weight gain by altering lipid homeostasis and promoting adipogenesis and lipid …

Caveolin: a new link between diabetes and AD

A Surguchov - Cellular and molecular neurobiology, 2020 - Springer
Alzheimer's disease (AD) and type 2 diabetes mellitus (T2D) are highly prevalent aging-
related diseases associated with significant morbidity and mortality. Patients with T2D have …

Caveolin 1 modulates aldosterone‐mediated pathways of glucose and lipid homeostasis

R Baudrand, N Gupta, AE Garza, A Vaidya… - Journal of the …, 2016 - Am Heart Assoc
Background Overactivation of the aldosterone and mineralocorticoid receptor (MR) pathway
is associated with hyperglycemia and dyslipidemia. Caveolin 1 (cav‐1) is involved in …

Genomic scan of selective sweeps in Djallonké (West African Dwarf) sheep shed light on adaptation to harsh environments

I Álvarez, I Fernández, A Traoré, L Pérez-Pardal… - Scientific Reports, 2020 - nature.com
Abstract The Djallonké (West African Dwarf) sheep is a small-sized haired sheep resulting
from a costly evolutionary process of natural adaptation to the harsh environment of West …

Interplay between caveolin-1 and mineralocorticoid receptor in cardiometabolic disease

K Czarzasta, LH Pojoga - Journal of Endocrinology, 2024 - joe.bioscientifica.com
Over the past decades, research has clearly established the important role of the
mineralocorticoid receptor (MR) in both renal and extra-renal tissues. Recently, caveolin-1 …

The genetic basis of obesity complications

K Skrypnik, J Suliburska, D Skrypnik… - Acta scientiarum …, 2017 - food.actapol.net
Intensive research is currently being performed into the genetic background of excess body
mass compli-cations such as diabetes, cardiovascular disorders, especially atherosclerosis …