Endocrine disrupting chemicals: exposure, effects on human health, mechanism of action, models for testing and strategies for prevention
Abstract Endocrine Disrupting Chemicals (EDCs) are a global problem for environmental
and human health. They are defined as “an exogenous chemical, or mixture of chemicals …
and human health. They are defined as “an exogenous chemical, or mixture of chemicals …
Physical activity, cardiorespiratory fitness, and the metabolic syndrome
J Myers, P Kokkinos, E Nyelin - Nutrients, 2019 - mdpi.com
Both observational and interventional studies suggest an important role for physical activity
and higher fitness in mitigating the metabolic syndrome. Each component of the metabolic …
and higher fitness in mitigating the metabolic syndrome. Each component of the metabolic …
Genetics of human primary hypertension: focus on hormonal mechanisms
W Manosroi, GH Williams - Endocrine reviews, 2019 - academic.oup.com
Increasingly, primary hypertension is being considered a syndrome and not a disease, with
the individual causes (diseases) having a common sign—an elevated blood pressure. To …
the individual causes (diseases) having a common sign—an elevated blood pressure. To …
Role of Caveolin‐1 in diabetes and its complications
It is estimated that in 2017 there were 451 million people with diabetes worldwide. These
figures are expected to increase to 693 million by 2045; thus, innovative preventative …
figures are expected to increase to 693 million by 2045; thus, innovative preventative …
Obesogenic endocrine disruptors and obesity: myths and truths
Obesogenic endocrine disruptors, also known as obesogens, are chemicals potentially
involved in weight gain by altering lipid homeostasis and promoting adipogenesis and lipid …
involved in weight gain by altering lipid homeostasis and promoting adipogenesis and lipid …
Caveolin: a new link between diabetes and AD
A Surguchov - Cellular and molecular neurobiology, 2020 - Springer
Alzheimer's disease (AD) and type 2 diabetes mellitus (T2D) are highly prevalent aging-
related diseases associated with significant morbidity and mortality. Patients with T2D have …
related diseases associated with significant morbidity and mortality. Patients with T2D have …
Caveolin 1 modulates aldosterone‐mediated pathways of glucose and lipid homeostasis
Background Overactivation of the aldosterone and mineralocorticoid receptor (MR) pathway
is associated with hyperglycemia and dyslipidemia. Caveolin 1 (cav‐1) is involved in …
is associated with hyperglycemia and dyslipidemia. Caveolin 1 (cav‐1) is involved in …
Genomic scan of selective sweeps in Djallonké (West African Dwarf) sheep shed light on adaptation to harsh environments
I Álvarez, I Fernández, A Traoré, L Pérez-Pardal… - Scientific Reports, 2020 - nature.com
Abstract The Djallonké (West African Dwarf) sheep is a small-sized haired sheep resulting
from a costly evolutionary process of natural adaptation to the harsh environment of West …
from a costly evolutionary process of natural adaptation to the harsh environment of West …
Interplay between caveolin-1 and mineralocorticoid receptor in cardiometabolic disease
K Czarzasta, LH Pojoga - Journal of Endocrinology, 2024 - joe.bioscientifica.com
Over the past decades, research has clearly established the important role of the
mineralocorticoid receptor (MR) in both renal and extra-renal tissues. Recently, caveolin-1 …
mineralocorticoid receptor (MR) in both renal and extra-renal tissues. Recently, caveolin-1 …
The genetic basis of obesity complications
K Skrypnik, J Suliburska, D Skrypnik… - Acta scientiarum …, 2017 - food.actapol.net
Intensive research is currently being performed into the genetic background of excess body
mass compli-cations such as diabetes, cardiovascular disorders, especially atherosclerosis …
mass compli-cations such as diabetes, cardiovascular disorders, especially atherosclerosis …