Emerging insights into the roles of ANGPTL8 beyond glucose and lipid metabolism

H Ye, Q Zong, H Zou, R Zhang - Frontiers in Physiology, 2023 - frontiersin.org
Angiopoietin-like protein 8 (ANGPTL8) is a secreted protein predominantly expressed in
liver and adipose tissue. ANGPTL8 modulates the clearance of triglycerides (TGs) by …

Contribution of biomarkers for pancreatic cancer-associated new-onset diabetes to pancreatic cancer screening

Z Zhang, W Qin, Y Sun - Pathology-Research and Practice, 2018 - Elsevier
Abstract Background Pancreatic cancer (PaC) is one of the deadliest types of tumor, and it is
regarded as a fatal disease, with a 5-year survival rate less than 10%. Most clinical …

[HTML][HTML] Impact of a post-lifestyle modification program in circulating angiopoietin-like proteins in Arab adolescents

MM Alenazi, S Sabico, AM Alnaami, K Wani… - Journal of King Saud …, 2024 - Elsevier
This study investigated the differences and associations between serum levels of
angiopoietin-like (ANGPTL) 3, ANGPTL4, and ANGPTL8 in Saudi adolescents with varying …

[HTML][HTML] Anti proliferative and apoptotic effects on pancreatic cancer cell lines indicate new roles for ANGPTL8 (Betatrophin)

F Taherkhani, KM Hosseini, S Zebardast… - … and Molecular Biology, 2020 - SciELO Brasil
Despite considerable advances, the treatment of pancreatic cancer (PC) still requires much
effort. Unusual regulation of the Wnt and apoptotic signaling pathways is widespread in …

The role of serum β-trophin and endostatin in patients with polycystic ovary syndrome: Are they correlated?

W Gong, A Bilixzi, X Wang, Y Lu, L Wan, L Han - BMC Women's Health, 2021 - Springer
Background It's necessary to investigate the serum β-trophin and endostatin (ES) level and
its influencing factors in patients with newly diagnosed polycystic ovary syndrome (PCOS) …

The potential role of betatrophin in hepatocellular carcinoma and metabolic syndrome

H Susanto, A Aulanni'am, CH Wang… - Journal of Physics …, 2019 - iopscience.iop.org
Metabolic syndrome is a fundamental health problem worldwide induced by obesity and
T2DM. Obesity linked long-standing diabetes was established as a crucial event in cancer …

Protein-based biomaterial marker in metabolic syndrome and colorectal cancer: a preliminary clinical study of betatrophin expression in Javanese ethnic

H Susanto, A Taufiq, D Listyorini… - IOP Conference …, 2019 - iopscience.iop.org
The presence of specific and unique chemical structure of a protein with their bioavailability
properties provide a hallmark of the essential contribution of the biomaterials. Protein-based …

Further Decoding the Molecular Relationship Between Pancreatic Adenocarcinoma and Diabetes Mellitus

RH Moreland III, S Khan - 2022 - scholarworks.utrgv.edu
Pancreatic ductal adenocarcinoma (PDAC) is a devastating malignancy, especially as there
are no current reliable methods of screening. Recently literature reports a significant …

Elevated Circulating Levels of N-Acetyl-Seryl-Aspartyl-Lysyl-Proline (AcSDKP) Involved in Pancreatic Cancer Development

H Susanto, JDT Purnomo, CC Chen, CH Wang - 2020 - researchsquare.com
Background: Pancreatic cancer is the fourth leading cause of patient mortality with poor
early prognosis. Lack of symptoms as early detection of this cancer has become the major …

Betatrophin expression in chronic hepatitis c patients: Does contribute to liver injury-linked metabolic syndrome and hepatocellular carcinoma development?

H Susanto, NS Liou, B Pratomo… - AIP Conference …, 2020 - pubs.aip.org
The epidemiologic evidence has been proved that chronic hepatitis C (CHC) infection may
significantly contribute to the progression of hepatocellular carcinoma (HCC). Moreover, the …