Mitochondria are highly dynamic organelles that participate in ATP generation and involve
calcium homeostasis, oxidative stress response, and apoptosis. Dysfunctional or damaged …

Degradation of mitochondria via a selective form of autophagy, named mitophagy, is a
fundamental mechanism conserved from yeast to humans that regulates mitochondrial …

Mitochondria are dynamic organelles with multiple functions. They participate in necrotic cell
death and programmed apoptotic, and are crucial for cell metabolism and survival …

Drug resistance represents a major obstacle in cancer management, and the mechanisms
underlying stress adaptation of cancer cells in response to therapy-induced hostile …

Mitochondria are essential organelles that execute and coordinate various metabolic
processes in the cell. Mitochondrial dysfunction severely affects cell fitness and contributes …

Mitochondria are central hubs of cellular metabolism that also play key roles in signaling
and disease. It is therefore fundamentally important that mitochondrial quality and activity …

Mitophagy is an evolutionarily conserved cellular process to remove dysfunctional or
superfluous mitochondria, thus fine-tuning mitochondrial number and preserving energy …

Mitochondria play key roles in bioenergetics, metabolism, and signaling; therefore, stable
mitochondrial function is essential for cell survival, particularly in energy-intensive neuronal …

Background Small cell lung cancer (SCLC) is the most aggressive subtype of lung cancer.
Although most patients are initially sensitive to first-line combination chemotherapy with …

With the growing prevalence of cardiovascular disease (CVD), there is an urgent need to
explore non-conventional therapeutic measures to alleviate the burden of CVD on global …