C–H activation has emerged as a viable alternative to traditional C–C bond forming
reactions such as the Suzuki–Miyaura, Stille, Negishi and others. However, C–H activation …

Benzocoumarins are coumarins with a phenyl group bonded to 3, 4-, 5, 6-, 6, 7-, or 7, 8-
positions. Over the past years, significant efforts have been made not only to isolate the …

An efficient domino Pd-catalyzed transformation of simple ortho-bromobenzyl tertiary
alcohols to chromenes is presented. Their formation is believed to proceed via the formation …

A series of 4-phenylcoumarin derivatives was synthesized and evaluated for their cellular
anti-HIV-1 and HIV-2 activities as well as their inhibitory effects against HIV-1 reverse …

Pyrones, pyridones and quinolones represent classes of molecules with remarkable and
diverse biological activity. The introduction of a trifluoromethyl group to a molecule can have …

Pyrones are important structural units in natural products and synthetic functional molecules.
Here, we report a carbene‐catalyzed oxidative [3+ 3] cycloaddition reaction between enals …

The first direct transition metal‐free access to 3, 6‐disubstituted α‐pyrones from α‐chloro
aldehydes and β‐tosyl enones is reported. The reactions proceed via the Michael …

Trisubstituted α-pyrones are obtained by a Pd-catalyzed three-component, single-flask
operation via an α-arylation, subsequent α-alkenylation, alkene isomerization, and dienolate …

An efficient metal-free approach for the synthesis of functionalized biaryl-cored
diarylmethanes is described by the ring transformation of 2H-pyran-2-ones using 4 …

Direct arylation represents a favourable alternative to traditional cross‐coupling reactions
and has found widespread use with simple aryls and robust heterocycles. Herein a direct …