Hematopoiesis and the bacterial microbiome

H Yan, MT Baldridge, KY King - Blood, The Journal of the …, 2018 - ashpublications.org
Recent studies have revealed that the intestinal bacterial microbiome plays an important
role in the regulation of hematopoiesis. A correlation between adverse hematologic effects …

[HTML][HTML] Mass cytometry for the assessment of immune reconstitution after hematopoietic stem cell transplantation

L Stern, H McGuire, S Avdic, S Rizzetto… - Frontiers in …, 2018 - frontiersin.org
Mass cytometry, or Cytometry by Time-Of-Flight, is a powerful new platform for high-
dimensional single-cell analysis of the immune system. It enables the simultaneous …

[HTML][HTML] Nutritional support from the intestinal microbiota improves hematopoietic reconstitution after bone marrow transplantation in mice

A Staffas, MB da Silva, AE Slingerland, A Lazrak… - Cell host & …, 2018 - cell.com
Bone marrow transplantation (BMT) offers curative potential for patients with high-risk
hematologic malignancies, but the post-transplantation period is characterized by profound …

[HTML][HTML] Severe infections after unrelated donor allogeneic hematopoietic stem cell transplantation in adults: comparison of cord blood transplantation with peripheral …

R Parody, R Martino, M Rovira, L Vazquez… - Biology of blood and …, 2006 - Elsevier
We evaluated the occurrence of severe infections in 192 consecutive adult recipients of
volunteer unrelated donor allogeneic hematopoietic stem cell transplants, with a detailed …

[HTML][HTML] Immune reconstitution kinetics as an early predictor for mortality using various hematopoietic stem cell sources in children

IH Bartelink, SV Belitser, CAJ Knibbe, M Danhof… - Biology of blood and …, 2013 - Elsevier
The severity of complications of allogeneic hematopoietic stem cell transplantation (HSCT)
is governed mainly by the status of immune reconstitution. In this study, we investigated …

[HTML][HTML] Lymphocyte subset recovery and outcome after autologous hematopoietic stem cell transplantation for plasma cell myeloma

J Rueff, M Medinger, D Heim, J Passweg… - Biology of Blood and …, 2014 - Elsevier
Rapid immune reconstitution—particularly of natural killer cells (NK cells)—after allogeneic
hematopoietic stem cell transplantation (HSCT) is associated with protection from relapse …

Rapid helper T-cell recovery above 200× 106/l at 3 months correlates to successful transplant outcomes after allogeneic stem cell transplantation

DH Kim, SK Sohn, DI Won, NY Lee, JS Suh… - Bone marrow …, 2006 - nature.com
The current study evaluates the role of quantitative measurement of peripheral lymphocyte
subsets, especially CD4+ helper T-cell recovery, in predicting transplant outcomes including …

Adoptive therapy with CMV-specific cytotoxic T lymphocytes depends on baseline CD4+ immunity to mediate durable responses

VA Fabrizio, MI Rodriguez-Sanchez… - Blood …, 2021 - ashpublications.org
Adoptive cell therapy using cytomegalovirus (CMV)-specific cytotoxic T lymphocytes (CMV-
CTLs) has demonstrated efficacy posttransplant. Despite the predicted limited engraftment of …

[HTML][HTML] Absolute lymphocyte count on day 30 is a surrogate for robust hematopoietic recovery and strongly predicts outcome after T cell-depleted allogeneic stem cell …

BN Savani, S Mielke, K Rezvani, A Montero… - Biology of Blood and …, 2007 - Elsevier
Several studies have shown that a higher lymphocyte count 3-4 weeks after allogeneic stem
cell transplantation (SCT) is associated with better transplant outcome. However, the factors …

[HTML][HTML] Donor KIR Genes 2DL5A, 2DS1 and 3DS1 are associated with a reduced rate of leukemia relapse after HLA-identical sibling stem cell transplantation for …

K Stringaris, S Adams, M Uribe, R Eniafe… - Biology of Blood and …, 2010 - Elsevier
Stem cell transplantation (SCT) from a healthy donor can be curative for patients with
hematologic malignancies resistant to other treatments. Elimination of malignant cells …