Plant small RNAs: their biogenesis, regulatory roles, and functions

J Zhan, BC Meyers - Annual Review of Plant Biology, 2023 - annualreviews.org
Plant cells accumulate small RNA molecules that regulate plant development, genome
stability, and environmental responses. These small RNAs fall into three major classes …

Small RNA-mediated DNA methylation during plant reproduction

HT Chow, RA Mosher - The Plant Cell, 2023 - academic.oup.com
Reproductive tissues are a rich source of small RNAs, including several classes of short
interfering (si) RNAs that are restricted to this stage of development. In addition to RNA …

Moving targets: Mechanisms regulating siRNA production and DNA methylation during plant development

LM Martins, JA Law - Current Opinion in Plant Biology, 2023 - Elsevier
DNA methylation is a conserved modification that must be precisely regulated during
development to facilitate its roles in silencing transposable elements and regulating gene …

RNA polymerase pausing, stalling and bypass during transcription of damaged DNA: from molecular basis to functional consequences

A Agapov, A Olina, A Kulbachinskiy - Nucleic Acids Research, 2022 - academic.oup.com
Cellular DNA is continuously transcribed into RNA by multisubunit RNA polymerases
(RNAPs). The continuity of transcription can be disrupted by DNA lesions that arise from the …

CRISPR–Cas-mediated transcriptional control and epi-mutagenesis

J Gardiner, B Ghoshal, M Wang… - Plant physiology, 2022 - academic.oup.com
Tools for sequence-specific DNA binding have opened the door to new approaches in
investigating fundamental questions in biology and crop development. While there are …

Mating system is associated with seed phenotypes upon loss of RNA-directed DNA methylation in Brassicaceae

KJ Dew-Budd, HT Chow, T Kendall, BC David… - Plant …, 2024 - academic.oup.com
In plants, de novo DNA methylation is guided by 24-nt short interfering (si) RNAs in a
process called RNA-directed DNA methylation (RdDM). Primarily targeted at transposons …

Structure and mechanism of the plant RNA polymerase V

G Xie, X Du, H Hu, S Li, X Cao, SE Jacobsen, J Du - Science, 2023 - science.org
In addition to the conserved RNA polymerases I to III (Pols I to III) in eukaryotes, two atypical
polymerases, Pols IV and V, specifically produce noncoding RNA in the RNA-directed DNA …

Enzymatic reactions of AGO4 in RNA-directed DNA methylation: siRNA duplex loading, passenger strand elimination, target RNA slicing, and sliced target retention

F Wang, HY Huang, J Huang, J Singh… - Genes & …, 2023 - genesdev.cshlp.org
RNA-directed DNA methylation in plants is guided by 24-nt siRNAs generated in parallel
with 23-nt RNAs of unknown function. We show that 23-nt RNAs function as passenger …

Dynamic regulation of DNA methylation and histone modifications in response to abiotic stresses in plants

Y Liu, J Wang, B Liu, ZY Xu - Journal of Integrative Plant …, 2022 - Wiley Online Library
DNA methylation and histone modification are evolutionarily conserved epigenetic
modifications that are crucial for the expression regulation of abiotic stress‐responsive …

RNAi-based antiviral innate immunity in plants

L Jin, M Chen, M Xiang, Z Guo - Viruses, 2022 - mdpi.com
Multiple antiviral immunities were developed to defend against viral infection in hosts. RNA
interference (RNAi)-based antiviral innate immunity is evolutionarily conserved in …