Natural polymers have distinct advantages over synthetic polymers because of their
abundance, biocompatibility, and biodegradability. Tragacanth gum, an anionic …

Purpose: P-glycoprotein (P-gp; ABCB1), an integral membrane protein in the apical surface
of human intestinal epithelial cells, plays a crucial role in the intestinal transport and efflux …

Objective Carvacrol is one of the main pharmacologically active components of Thymus
vulgaris essential oil, which has shown several therapeutic effects. Because of liquid nature …

Microcrystalline cellulose (MCC) is widely regarded as the excellent choice to manufacture
pellets via wet extrusion–spheronisation (ES) process due to its excellent water uptake …

In pharmaceutical industries, pellets are multiparticulate dosage form which was formed by
the agglomeration of fine powdered excipient and drugs together that leads to the formation …

The objective of this study was to develop and evaluate mucoadhesive microsphere of
diclofenac sodium with natural gums for sustained delivery. Guar gum and tragacanth were …

The objective was to formulate itopride HCl (ITP) extended release matrix-coated pellets by
extrusion–spheronization and to investigate the influence of concentration and viscosity …

For decades, a wide range of polymeric materials have been used in pharmaceutical
technology. Modern drug delivery systems based on biocompatible and biodegradable …

Natural polymers are continuously investigated for use in pharmaceutical and tissue
engineering applications due to the renewability of their supply. Besides the conventional …

Background: In order to prove the validity of a new formulation, a considerable amount of
effort is required to study bioequivalence, which not only increases the burden of carrying …