With the advent of multiomics, software capable of multidimensional enrichment analysis
has become increasingly crucial for uncovering gene set variations in biological processes …

Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis. Cancer-associated
fibroblasts (CAFs) are recognized potential therapeutic targets, but poor understanding of …

The establishment of an early pro-regenerative niche is crucial for tissue regeneration,.
Gasdermin D (GSDMD)-dependent pyroptosis accounts for the release of inflammatory …

Optical pooled screening (OPS) is a scalable method for linking image-based phenotypes
with cellular perturbations. However, it has thus far been restricted to relatively low-plex …

Background Cervical cancer (CC) is the fourth most common malignancy among women
globally and serves as the main cause of cancer-related deaths among women in …

Corticosteroid treatment (CST) failure is associated with poor outcomes for patients with
gastrointestinal (GI) graft-versus-host disease (GVHD). CST is intended to target the immune …

Background Tumor heterogeneity presents a formidable challenge in understanding the
mechanisms driving tumor progression and metastasis. The heterogeneity of hepatocellular …

Inflammation, fibrosis and metabolic stress critically promote heart failure with preserved
ejection fraction (HFpEF). Exposure to high-fat diet and nitric oxide synthase inhibitor N [w] …

Gene expression is orchestrated by transcription factors, which function within the context of
a three-dimensional genome. Zinc-finger protein 143 (ZNF143/ZFP143) is a transcription …

Deep learning models have been developed for various predictions in glioma; yet, they were
constrained by manual segmentation, task-specific design, or a lack of biological …