Innate and adaptive immunity during SARS-CoV-2 infection: biomolecular cellular markers and mechanisms

B Brown, V Ojha, I Fricke, SA Al-Sheboul, C Imarogbe… - Vaccines, 2023 - mdpi.com
The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Macrophage subsets and their role: co-relation with colony-stimulating factor-1 receptor and clinical relevance

S Yadav, A Priya, DR Borade, R Agrawal-Rajput - Immunologic Research, 2023 - Springer
Macrophages are one of the first innate immune cells to reach the site of infection or injury.
Diverse functions from the uptake of pathogen or antigen, its killing, and presentation, the …

Aryl hydrocarbon receptor: The master regulator of immune responses in allergic diseases

F Riaz, F Pan, P Wei - Frontiers in Immunology, 2022 - frontiersin.org
The aryl hydrocarbon receptor (AhR) is a widely studied ligand-activated cytosolic
transcriptional factor that has been associated with the initiation and progression of various …

COVID-19 pandemic: the delta variant, T-cell responses, and the efficacy of developing vaccines

B Biswas, S Chattopadhyay, S Hazra, AK Hansda… - Inflammation …, 2022 - Springer
Background The mayhem COVID-19 that was ushered by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV2) was declared pandemic by the World Health …

Koumine alleviates rheumatoid arthritis by regulating macrophage polarization

Y Lin, F Zheng, B Xiong, Z Chen, S Chen… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance The imbalance between M1-and M2-polarized
macrophages is one of the major pathophysiological changes in RA. Therefore, targeted …

Allergic rhinitis: pathophysiology and treatment focusing on mast cells

Y Zoabi, F Levi-Schaffer, R Eliashar - Biomedicines, 2022 - mdpi.com
Allergic rhinitis (AR) is a common rhinopathy that affects up to 30% of the adult population. It
is defined as an inflammation of the nasal mucosa, develops in allergic individuals, and is …

Circulating MMP‐12 as potential biomarker in evaluating disease severity and efficacy of sublingual immunotherapy in allergic rhinitis

Y Zhou, M Xu, W Gong, X Kang, R Guo… - Mediators of …, 2022 - Wiley Online Library
Background. Allergic rhinitis (AR) is a highly heterogeneous disease, and allergen‐specific
immunotherapy (AIT) is an effective treatment. This study aims to evaluate the circulating …

Expected impact of immunomodulatory agents during pregnancy: a newborn's perspective

Y Luo, D Acevedo, N Baños, A Pluma… - Pediatric Allergy and …, 2023 - Wiley Online Library
The neonatal immune ontogeny begins during pregnancy to ensure that the neonate is well‐
suited for perinatal life. It prioritizes Th2/M2 and regulatory responses over Th/M1 activity to …

Interactions between macrophages and mast cells in the female reproductive system

N Lampiasi - International Journal of Molecular Sciences, 2022 - mdpi.com
Mast cells (MCs) and macrophages (Mϕs) are innate immune cells that differentiate from
early common myeloid precursors and reside in all body tissues. MCs have a unique …

[HTML][HTML] Lirentelimab for severe and chronic forms of allergic conjunctivitis

SD Anesi, J Tauber, QD Nguyen, P Chang… - Journal of Allergy and …, 2022 - Elsevier
Background Allergic conjunctivitis (AC) is an ocular inflammatory disease with symptoms
driven by eosinophils and mast cells. Allergic comorbidities are common. Current treatments …