Purpose: To compare luteinizing hormone-releasing hormone (LHRH) agonists with
orchiectomy or diethylstilbestrol, and to compare antiandrogens with any of these three …

Background: In US men, prostate cancer is the most common noncutaneous cancer and the
second leading cause of cancer death. Screening for prostate cancer is controversial …

Health care decisions are increasingly being made on research-based evidence rather than
on expert opinion or clinical experience alone. Systematic reviews represent a rigorous …

Abstract BACKGROUND. The American Cancer Society, the Centers for Disease Control
and Prevention, the National Cancer Institute, and the North American Association of Central …

This report presents the recommendations of the WHO Expert Committee responsible for
updating the WHO Model Lists of Essential Medicines.. The goal of the meeting was to …

Purpose: To examine the effect of hospital and surgeon volume on postoperative outcomes
and to determine whether hospital or surgeon volume is the stronger predictor. Patients and …

Poly (lactic acid) and its copolymers have revolutionized the field of drug delivery due to
their excellent biocompatibility and tunable physico-chemical properties. These copolymers …

BACKGROUND The current systematic review and meta‐analysis compared monotherapy
and combined androgen blockade in the treatment of men with advanced prostate …

PURPOSE: To examine variation in men's long-term regret of treatment decisions, ie,
surgical versus chemical castration, for metastatic prostate cancer and its associations with …

Over its natural course, prostate cancer is a heterogeneous tumour with a generally slow but
constant rate of growth. The androgen dependence of the prostate gland was demonstrated …