Osteoinduction of bone grafting materials for bone repair and regeneration
E García-Gareta, MJ Coathup, GW Blunn - Bone, 2015 - Elsevier
Regeneration of bone defects caused by trauma, infection, tumours or inherent genetic
disorders is a clinical challenge that usually necessitates bone grafting materials …
disorders is a clinical challenge that usually necessitates bone grafting materials …
Initiation and early control of tissue regeneration–bone healing as a model system for tissue regeneration
K Schmidt-Bleek, A Petersen, A Dienelt… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Tissue regeneration in itself is a fascinating process that promises repeated
renewal of tissue and organs. Areas covered: This article aims to illustrate the different …
renewal of tissue and organs. Areas covered: This article aims to illustrate the different …
[HTML][HTML] Release and bioactivity of bone morphogenetic protein-2 are affected by scaffold binding techniques in vitro and in vivo
A low dose of 1 μg rhBMP-2 was immobilised by four different functionalising techniques on
recently developed poly (l-lactide)-co-(ε-caprolactone)[(poly (LLA-co-CL)] scaffolds. It was …
recently developed poly (l-lactide)-co-(ε-caprolactone)[(poly (LLA-co-CL)] scaffolds. It was …
Taking cues from the extracellular matrix to design bone-mimetic regenerative scaffolds
AS Curry, NW Pensa, AM Barlow, SL Bellis - Matrix Biology, 2016 - Elsevier
There is an ongoing need for effective materials that can replace autologous bone grafts in
the clinical treatment of bone injuries and deficiencies. In recent years, research efforts have …
the clinical treatment of bone injuries and deficiencies. In recent years, research efforts have …
Osteoinductivity and biomechanical assessment of a 3D printed demineralized bone matrix-ceramic composite in a rat spine fusion model
We recently developed a recombinant growth factor-free bone regenerative scaffold
composed of stoichiometric hydroxyapatite (HA) ceramic particles and human demineralized …
composed of stoichiometric hydroxyapatite (HA) ceramic particles and human demineralized …
Cervical total disc replacement: long-term outcomes
G Callanan, KE Radcliff - Neurosurgery Clinics, 2021 - neurosurgery.theclinics.com
Background Disorder of the cervical spine is a common clinical problem encountered by
physicians. The cervical spine is composed of 7 vertebrae. The subaxial cervical spine is …
physicians. The cervical spine is composed of 7 vertebrae. The subaxial cervical spine is …
The effect of dose on rhBMP-2 signaling, delivered via collagen sponge, on osteoclast activation and in vivo bone resorption
While recombinant human bone morphogenetic protein (rhBMP)-2-based bone therapy
presents potential osteoinductivity, it also leads concern due to transient osteoclast …
presents potential osteoinductivity, it also leads concern due to transient osteoclast …
Acceleration of bone regeneration by BMP‐2‐loaded collagenated biphasic calcium phosphate in rabbit sinus
JS Kim, JK Cha, AR Cho, MS Kim… - … implant dentistry and …, 2015 - Wiley Online Library
Purpose The objective of this study was to determine the effectiveness of collagenated
biphasic calcium phosphate (CBCP) as a carrier for bone morphogenetic protein‐2 (BMP‐2) …
biphasic calcium phosphate (CBCP) as a carrier for bone morphogenetic protein‐2 (BMP‐2) …
Investigating the osteoinductive potential of a decellularized xenograft bone substitute
Bone grafting is the second most common tissue transplantation procedure worldwide. One
of the alternative methods for bone repair under investigation is a tissue-engineered bone …
of the alternative methods for bone repair under investigation is a tissue-engineered bone …
Biologics in spine arthrodesis
A Kannan, SNM Dodwad, WK Hsu - Clinical Spine Surgery, 2015 - journals.lww.com
Spine fusion is a tool used in the treatment of spine trauma, tumors, and degenerative
disorders. Poor outcomes related to failure of fusion, however, have directed the interests of …
disorders. Poor outcomes related to failure of fusion, however, have directed the interests of …