Building muscle: molecular regulation of myogenesis

CF Bentzinger, YX Wang… - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
The genesis of skeletal muscle during embryonic development and postnatal life serves as a
paradigm for stem and progenitor cell maintenance, lineage specification, and terminal …

The genetics of vertebrate myogenesis

RJ Bryson-Richardson, PD Currie - Nature Reviews Genetics, 2008 - nature.com
The molecular, genetic and cellular bases for skeletal muscle growth and regeneration have
been recently documented in a number of vertebrate species. These studies highlight the …

Mesp1 patterns mesoderm into cardiac, hematopoietic, or skeletal myogenic progenitors in a context-dependent manner

SSK Chan, X Shi, A Toyama, RW Arpke, A Dandapat… - Cell stem cell, 2013 - cell.com
Mesp1 is regarded as the master regulator of cardiovascular development, initiating the
cardiac transcription factor cascade to direct the generation of cardiac mesoderm. To define …

[HTML][HTML] Muscle satellite cells are a functionally heterogeneous population in both somite-derived and branchiomeric muscles

Y Ono, L Boldrin, P Knopp, JE Morgan… - Developmental biology, 2010 - Elsevier
Skeletal muscles of body and limb are derived from somites, but most head muscles
originate from cranial mesoderm. The resident stem cells of muscle are satellite cells, which …

Distinct and dynamic myogenic populations in the vertebrate embryo

M Buckingham, SD Vincent - Current opinion in genetics & development, 2009 - Elsevier
Myogenic cells in the body of vertebrates derive from the dorsal somite, the dermomyotome,
where multipotent cells are present. Regulation of cell fate choice is discussed, as is that of …

Extensive size variability of the GGGGCC expansion in C9orf72 in both neuronal and non-neuronal tissues in 18 patients with ALS or FTD

A Nordin, C Akimoto, A Wuolikainen… - Human molecular …, 2015 - academic.oup.com
A GGGGCC-repeat expansion in C9orf72 is the most common genetic cause of amyotrophic
lateral sclerosis (ALS) and frontotemporal dementia (FTD) among Caucasians. However …

Myoblasts derived from normal hESCs and dystrophic hiPSCs efficiently fuse with existing muscle fibers following transplantation

S Goudenege, C Lebel, NB Huot, C Dufour, I Fujii… - Molecular Therapy, 2012 - cell.com
Human embryonic stem cells (hESCs) and human-induced pluripotent stem cells (hiPSCs)
have an endless self-renewal capacity and can theoretically differentiate into all types of …

Mechanisms of skeletal muscle-tendon development and regeneration/healing as potential therapeutic targets

Y Yoshimoto, Y Oishi - Pharmacology & Therapeutics, 2023 - Elsevier
Skeletal muscle contraction is essential for the movement of our musculoskeletal system.
Tendons and ligaments that connect the skeletal muscles to bones in the correct position at …

Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells

GH Zhu, J Huang, Y Bi, Y Su, Y Tang, BC He, Y He… - Differentiation, 2009 - Elsevier
Differentiation of embryonic and adult myogenic progenitors undergoes a complex series of
cell rearrangements and specification events which are controlled by distinct gene …

Deregulation of the Protocadherin Gene FAT1 Alters Muscle Shapes: Implications for the Pathogenesis of Facioscapulohumeral Dystrophy

N Caruso, B Herberth, M Bartoli, F Puppo… - PLoS …, 2013 - journals.plos.org
Generation of skeletal muscles with forms adapted to their function is essential for normal
movement. Muscle shape is patterned by the coordinated polarity of collectively migrating …