Pfam: the protein families database

RD Finn, A Bateman, J Clements, P Coggill… - Nucleic acids …, 2014 - academic.oup.com
Pfam, available via servers in the UK (http://pfam. sanger. ac. uk/) and the USA (http://pfam.
janelia. org/), is a widely used database of protein families, containing 14 831 manually …

Occurrence, classification, and biological function of hydrogenases: an overview

PM Vignais, B Billoud - Chemical reviews, 2007 - ACS Publications
If the atmosphere of the early Earth was hydrogen-rich, 1 it is reasonable to think that
hydrogenases, the enzymes enabling cells to use molecular hydrogen, were probably …

SingleCellSignalR: inference of intercellular networks from single-cell transcriptomics

S Cabello-Aguilar, M Alame… - Nucleic acids …, 2020 - academic.oup.com
Single-cell transcriptomics offers unprecedented opportunities to infer the ligand–receptor
(LR) interactions underlying cellular networks. We introduce a new, curated LR database …

MitoCarta2. 0: an updated inventory of mammalian mitochondrial proteins

SE Calvo, KR Clauser, VK Mootha - Nucleic acids research, 2016 - academic.oup.com
Mitochondria are complex organelles that house essential pathways involved in energy
metabolism, ion homeostasis, signalling and apoptosis. To understand mitochondrial …

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

PV Hornbeck, B Zhang, B Murray… - Nucleic acids …, 2015 - academic.oup.com
Abstract PhosphoSitePlus®(PSP, http://www. phosphosite. org/), a knowledgebase
dedicated to mammalian post-translational modifications (PTMs), contains over 330 000 non …

Comparison and integration of deleteriousness prediction methods for nonsynonymous SNVs in whole exome sequencing studies

C Dong, P Wei, X Jian, R Gibbs… - Human molecular …, 2015 - academic.oup.com
Accurate deleteriousness prediction for nonsynonymous variants is crucial for distinguishing
pathogenic mutations from background polymorphisms in whole exome sequencing (WES) …

AF2Complex predicts direct physical interactions in multimeric proteins with deep learning

M Gao, D Nakajima An, JM Parks, J Skolnick - Nature communications, 2022 - nature.com
Accurate descriptions of protein-protein interactions are essential for understanding
biological systems. Remarkably accurate atomic structures have been recently computed for …

PredictSNP: robust and accurate consensus classifier for prediction of disease-related mutations

J Bendl, J Stourac, O Salanda, A Pavelka… - PLoS computational …, 2014 - journals.plos.org
Single nucleotide variants represent a prevalent form of genetic variation. Mutations in the
coding regions are frequently associated with the development of various genetic diseases …

The reliability of metagenome-assembled genomes (MAGs) in representing natural populations: insights from comparing MAGs against isolate genomes derived from …

A Meziti, LM Rodriguez-R, JK Hatt… - Applied and …, 2021 - Am Soc Microbiol
The recovery of metagenome-assembled genomes (MAGs) from metagenomic data has
recently become a common task for microbial studies. The strengths and limitations of the …

Robust and accurate prediction of residue–residue interactions across protein interfaces using evolutionary information

S Ovchinnikov, H Kamisetty, D Baker - elife, 2014 - elifesciences.org
Do the amino acid sequence identities of residues that make contact across protein
interfaces covary during evolution? If so, such covariance could be used to predict contacts …