The presence of most of the atoms involved in the building up of living cells can be
explained by their intrinsic physico-chemical properties. Yet, the involvement of the alkali …

Prokaryotes have evolved a multitude of defense systems to protect against phage
predation. Some of these resemble eukaryotic genes involved in antiviral responses. Here …

Entamoeba histolytica, a microaerophilic protozoan parasite, possesses mitosomes.
Mitosomes are mitochondrion-related organelles that have largely lost typical mitochondrial …

In many organisms, 3′-phosphoadenosine 5′-phosphate (PAP) is a product of two
reactions in the sulfur activation pathway. The sulfurylation of biomolecules, catalyzed by …

NADP (H)/NAD (H) homeostasis has long been identified to play a pivotal role in the
mitigation of reactive oxygen stress (ROS) in the intracellular milieu and is therefore critical …

Entamoeba histolytica is an enteric protozoan parasite that causes amoebic dysentery and
liver abscesses. Infection usually takes place by consuming food or water contaminated with …

Inositol polyphosphate 1-phosphatase from Entamoeba histolytica (EhIPPase) is an Mg2+-
dependent and Li+-sensitive enzyme that catalyzes the hydrolysis of inositol 1, 4 …

The following studies use structural biology approaches to explore enzymes involved in
sulfur metabolism and RNA editing. Three separate projects focus on completely different …

The stationary-phase survival protein SurE from Brucella abortus (BaSurE) is a metal-
dependent phosphatase that is essential for the survival of this bacterium in the stationary …