Ischemic stroke generates an immune response that contributes to neuronal loss as well as
tissue repair. This is a complex process involving a range of cell types and effector …

Over 1.5 million deaths worldwide are caused by neurocardiogenic syndromes.
Furthermore, the consequences of deleterious brain-heart interactions are not limited to fatal …

After ischemic stroke, there is a significant burden of cardiovascular complications, both in
the acute and chronic phase. Severe adverse cardiac events occur in 10% to 20% of …

Ischemic stroke (IS) produces a powerful inflammatory cascade in the brain, resulting in the
occurrence of neuroinflammation. Neuroinflammation is triggered not only by resident …

Extracellular vesicles (EVs) are extremely versatile naturally occurring membrane particles
that convey complex signals between cells. EVs of different cellular sources are capable of …

The social and public health burdens of ischemic stroke have been increasing worldwide. In
addition to focal brain damage, acute ischemic stroke (AIS) provokes systemic abnormalities …

Stroke is a leading cause of mortality and morbidity, with long-term debilitating effects.
Accumulating evidence from experimental studies as well as observational studies in …

Cerebral-cardiac syndrome (CCS) refers to cardiac dysfunction following varying brain
injuries. Ischemic stroke is strongly evidenced to induce CCS characterizing as arrhythmia …

Aging and aging‐related CNS diseases are associated with inflammatory status. As an
efficient amplifier of immune responses, inflammasome is activated and played detrimental …

Stroke is followed by an intricate immune interaction involving the engagement of multiple
immune cells, including neutrophils. As one of the first responders recruited to the brain, the …