Schwannomas may occur spontaneously, or in the context of a familial tumor syndrome such
as neurofibromatosis type 2 (NF 2), schwannomatosis and C arney's complex …

Schwannomas are tumors of the peripheral nervous system, consisting of different cell types.
These include tumorigenic Schwann cells, axons, macrophages, T cells, fibroblasts, blood …

Abstract Neurofibromatosis type 2 (NF2) is a genetic condition marked by the development
of multiple benign tumors in the nervous system. The most common tumors associated with …

Background Inflammation is hypothesized to be a key event in the growth of sporadic
vestibular schwannoma (VS). In this study we sought to investigate the relationship between …

Vestibular schwannomas are tumors arising from the vestibulocochlear nerve at the
cerebellopontine angle. Their proximity to eloquent brainstem structures means that the …

Loss of the Merlin tumor suppressor and activation of the Hippo signaling pathway play
major roles in the control of cell proliferation and tumorigenesis. We have identified …

Schwannomas are slow-growing benign neoplasms that develop throughout the body
causing pain, sensory/motor dysfunction, and death. Because bacterial immunotherapy has …

Bilateral vestibular schwannoma is the hallmark of NF2-related schwannomatosis, a rare
tumour predisposition syndrome associated with a lifetime of surgical interventions …

Schwannoma tumours typically arise on the eighth cranial nerve and are mostly caused by
loss of the tumour suppressor Merlin (NF2). There are no approved chemotherapies for …

Vestibular schwannomas (VSs, also known as acoustic neuromas) are relatively rare benign
brain tumors stem from the Schwann cells of the eighth cranial nerve. Tumor growth is the …