[HTML][HTML] Biomarkers in renal transplantation: An updated review

M Salvadori, A Tsalouchos - World journal of transplantation, 2017 - ncbi.nlm.nih.gov
Genomics, proteomics and molecular biology lead to tremendous advances in all fields of
medical sciences. Among these the finding of biomarkers as non invasive indicators of …

Molecular diagnostics in transplantation

M Naesens, MM Sarwal - Nature Reviews Nephrology, 2010 - nature.com
The past few decades are characterized by an explosive evolution of genetics and
molecular cell biology. Advances in chemistry and engineering have enabled increased …

Immunosuppression withdrawal in liver transplant recipients on sirolimus

J Levitsky, BE Burrell, S Kanaparthi, LA Turka… - …, 2020 - Wiley Online Library
BACKGROUND AND AIMS As conversion from calcineurin inhibitor to sirolimus (SRL), a
mechanistic target of rapamycin inhibitor (mTOR‐I), has been shown to enhance …

Gene expression analysis reveals schizophrenia-associated dysregulation of immune pathways in peripheral blood mononuclear cells

EJ Gardiner, MJ Cairns, B Liu, NJ Beveridge… - Journal of psychiatric …, 2013 - Elsevier
Peripheral blood mononuclear cells (PBMCs) represent an accessible tissue source for
gene expression profiling in schizophrenia that could provide insight into the molecular …

Establishing biomarkers in transplant medicine: a critical review of current approaches

D Anglicheau, M Naesens, M Essig, W Gwinner… - …, 2016 - journals.lww.com
Although the management of kidney transplant recipients has greatly improved over recent
decades, the assessment of individual risks remains highly imperfect. Individualized …

Physical characterization of the “immunosignaturing effect”

P Stafford, R Halperin, JB Legutki, DM Magee… - Molecular & Cellular …, 2012 - ASBMB
Identifying new, effective biomarkers for diseases is proving to be a challenging problem.
We have proposed that antibodies may offer a solution to this problem. The physical features …

Proteomic signatures in plasma during early acute renal allograft rejection

GVC Freue, M Sasaki, A Meredith, OP Günther… - Molecular & Cellular …, 2010 - ASBMB
Acute graft rejection is an important clinical problem in renal transplantation and an adverse
predictor for long term graft survival. Plasma biomarkers may offer an important option for …

Biomarkers in solid organ transplantation: establishing personalized transplantation medicine

S Roedder, M Vitalone, P Khatri, MM Sarwal - Genome Medicine, 2011 - Springer
Technological advances in molecular and in silico research have enabled significant
progress towards personalized transplantation medicine. It is now possible to conduct …

Contemporary biomarkers for renal transplantation: A narrative overview

D Novacescu, SC Latcu, R Bardan… - Journal of Personalized …, 2023 - mdpi.com
Renal transplantation (RT) is the preferred treatment for end-stage renal disease. However,
clinical challenges persist, ie, early detection of graft dysfunction, timely identification of …

[HTML][HTML] Activation of ERK accelerates repair of renal tubular epithelial cells, whereas it inhibits progression of fibrosis following ischemia/reperfusion injury

HS Jang, SJ Han, JI Kim, S Lee, JH Lipschutz… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Extracellular signal-regulated kinase (ERK) signals play important roles in cell death and
survival. However, the role of ERK in the repair process after injury remains to be defined in …