Recent advances in liver engineering with decellularized scaffold

Q Dai, W Jiang, F Huang, F Song, J Zhang… - … in Bioengineering and …, 2022 - frontiersin.org
Liver transplantation is currently the only effective treatment for patients with end-stage liver
disease; however, donor liver scarcity is a notable concern. As a result, extensive endeavors …

[HTML][HTML] Making human pancreatic islet organoids: Progresses on the cell origins, biomaterials and three-dimensional technologies

L Jiang, Y Shen, Y Liu, L Zhang, W Jiang - Theranostics, 2022 - ncbi.nlm.nih.gov
Diabetes is one of the most socially challenging health concerns. Even though islet
transplantation has shown promise for insulin-dependent diabetes, there is still no effective …

Tissue engineering of decellularized pancreas scaffolds for regenerative medicine in diabetes

LY Lim, SSL Ding, P Muthukumaran, SH Teoh, Y Koh… - Acta Biomaterialia, 2023 - Elsevier
Diabetes mellitus is a global disease requiring long-term treatment and monitoring. At
present, pancreas or islet transplantation is the only reliable treatment for achieving stable …

Stem cells as a source of pancreatic cells for production of 3D bioprinted bionic pancreas in the treatment of type 1 diabetes

M Wszoła, D Nitarska, P Cywoniuk, M Gomółka, M Klak - Cells, 2021 - mdpi.com
Type 1 diabetes (T1D) is the third most common autoimmune disease which develops due
to genetic and environmental risk factors. Often, intensive insulin therapy is insufficient, and …

[HTML][HTML] Bioengineering liver tissue by repopulation of decellularised scaffolds

Z Afzal, EL Huguet - World Journal of Hepatology, 2023 - ncbi.nlm.nih.gov
Liver transplantation is the only curative therapy for end stage liver disease, but is limited by
the organ shortage, and is associated with the adverse consequences of …

Solid fraction determines stiffness and viscosity in decellularized pancreatic tissues

J Snellings, E Keshi, P Tang, A Daneshgar… - Biomaterials …, 2022 - Elsevier
The role of extracellular matrix (ECM) composition and turnover in mechano-signaling and
the metamorphic fate of cells seeded into decellularized tissue can be elucidated by recent …

Toward a 3D Printed Perfusable Islet Embedding Structure: Technical Notes and Preliminary Results

E Keshi, P Tang, T Lam, S Moosburner… - … Engineering Part C …, 2023 - liebertpub.com
To date, islet transplantation to treat type 1 diabetes mellitus remains unsuccessful in long-
term follow-up, mainly due to failed engraftment and reconstruction of the islet niche …

Development and systematic evaluation of decellularization protocols in different application models for diaphragmatic tissue engineering

MN Andreas, AK Boehm, P Tang, S Moosburner… - Biomaterials …, 2023 - Elsevier
Background Tissue engineered bioscaffolds based on decellularized composites have
gained increasing interest for treatment of various diaphragmatic impairments, including …

Decellularized matrix bioscaffolds: implementation of native microenvironment in pancreatic tissue engineering

J Hashemi, G Barati, B Bibak - Pancreas, 2021 - journals.lww.com
Type 1 diabetes is an autoimmune disease, and its incidence is usually estimated in the
range of 5% to 10%. Currently, the administration of exogenous insulin is the standard of …

[HTML][HTML] 功能胰腺β 细胞获取与应用的研究进展

向桂, 齐阳, 刘清桂, 胡以平, 王敏君, 陈费 - 生物工程学报, 2022 - cjb.ijournals.cn
胰腺β 细胞生成和分泌的胰岛素对维持人体正常血糖起到关键作用, 胰岛素分泌不足或利用缺陷
将会导致糖尿病(diabetes mellitus, DM) 的发生. 经典的DM 治疗方法包括药物治疗和胰岛移植 …