Mechanisms for modulating anoikis resistance in cancer and the relevance of metabolic reprogramming

FO Adeshakin, AO Adeshakin, LO Afolabi, D Yan… - Frontiers in …, 2021 - frontiersin.org
The attachment of cells to the extracellular matrix (ECM) is the hallmark of structure–function
stability and well-being. ECM detachment in localized tumors precedes abnormal …

Lead phytochemicals for anticancer drug development

S Singh, B Sharma, SS Kanwar, A Kumar - Frontiers in plant science, 2016 - frontiersin.org
Cancer is a serious concern at present. A large number of patients die each year due to
cancer illnesses in spite of several interventions available. Development of an effective and …

Phosphatidylserine: A cancer cell targeting biomarker

B Sharma, SS Kanwar - Seminars in cancer biology, 2018 - Elsevier
Cancer is a leading cause of mortality and morbidity globally. Many prominent cancer-
associated molecules have been identified over the recent years which include EGFR …

[HTML][HTML] Microbial therapeutic enzymes: A promising area of biopharmaceuticals

M Vachher, A Sen, R Kapila, A Nigam - Current Research in Biotechnology, 2021 - Elsevier
Biopharmaceuticals is a rapidly emerging field that explores and employs biological
organisms and their products for therapeutic applications. Enzymes are remarkable …

Polymer-drug conjugate, a potential therapeutic to combat breast and lung cancer

S Alven, X Nqoro, B Buyana, BA Aderibigbe - Pharmaceutics, 2020 - mdpi.com
Cancer is a chronic disease that is responsible for the high death rate, globally. The
administration of anticancer drugs is one crucial approach that is employed for the treatment …

Microbial enzymes for deprivation of amino acid metabolism in malignant cells: biological strategy for cancer treatment

R Dhankhar, V Gupta, S Kumar, RK Kapoor… - Applied Microbiology and …, 2020 - Springer
Amino acid deprivation therapy (AADT) is emerging as a promising strategy for the
development of novel therapeutics against cancer. This biological therapy relies upon the …

Amino acid deprivation using enzymes as a targeted therapy for cancer and viral infections

HS Fernandes, CS Silva Teixeira… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Amino acid depletion in the blood serum is currently being exploited and
explored for therapies in tumors or viral infections that are auxotrophic for a certain amino …

Biologically active secondary metabolites and biotechnological applications of species of the family Chaetomiaceae (Sordariales): An updated review from 2016 to …

SRM Ibrahim, SGA Mohamed, IA Sindi… - Mycological …, 2021 - Springer
Fungi are eukaryotic organisms that have the ability to synthesize an enormous number of
metabolites with a vast diversity of chemical structures and bioactivities. Chaetomiaceae …

Nanoparticles formulations of artemisinin and derivatives as potential therapeutics for the treatment of cancer, leishmaniasis and malaria

S Alven, BA Aderibigbe - Pharmaceutics, 2020 - mdpi.com
Cancer, malaria, and leishmaniasis remain the deadly diseases around the world although
several strategies of treatment have been developed. However, most of the drugs used to …

Role of the oral microbiome, metabolic pathways, and novel diagnostic tools in intra-oral halitosis: a comprehensive update

LH Foo, P Balan, LM Pang, ML Laine… - Critical Reviews in …, 2021 - Taylor & Francis
Halitosis or oral malodor is one of the most common reasons for the patients' visit to the
dental clinic, ranking behind only dental caries and periodontitis. In the present times, where …