The regulation of vascular endothelial growth factor A (VEGF) is critical to
neovascularization in numerous tissues under physiological and pathological conditions …

Swarming or collective motion of living entities is one of the most common and spectacular
manifestations of living systems that have been extensively studied in recent years. A …

The vertebrate body displays a segmental organization that is most conspicuous in the
periodic organization of the vertebral column and peripheral nerves. This metameric …

Despite major scientific, medical and technological advances over the last few decades, a
cure for cancer remains elusive. The disease initiation is complex, and including initiation …

During development cells and tissues undergo changes in pattern and form that employ a
wider range of physical mechanisms than at any other time in an organism's life. This book …

We present a 3D multi-cell simulation of a generic simplification of vascular tumor growth
which can be easily extended and adapted to describe more specific vascular tumor types …

Gliomas are uniformly fatal forms of primary brain neoplasms that vary from low-to high-
grade (glioblastoma). Whereas low-grade gliomas are weakly angiogenic, glioblastomas …

This work describes the first cell-based model of tumor-induced angiogenesis. At the
extracellular level, the model describes diffusion, uptake, and decay of tumor-secreted pro …

Neuropilin 1 (Nrp1) is a coreceptor for vascular endothelial growth factor A165 (VEGF-A165,
VEGF-A164 in mice) and semaphorin 3A (SEMA3A). Nevertheless, Nrp1 null embryos …

In vitro cultures of endothelial cells are a widely used model system of the collective
behavior of endothelial cells during vasculogenesis and angiogenesis. When seeded in an …