Simple Summary During the last two decades, collaborative translational studies utilizing
novel methodologies have dramatically advanced our understanding of multiple myeloma …

Multiple myeloma (MM) is a hematologic malignancy characterized by the proliferation of
clonal plasma cells in the bone marrow (BM). It is known that early genetic mutations in post …

A sleepless night may feel awful in its aftermath, but sleep's revitalizing powers are
substantial, perpetuating the idea that convalescent sleep is a consequence-free …

Background Multiple myeloma (MM) is a heterogeneous disease with different patterns of
clonal evolution and a complex tumor microenvironment, representing a challenge for …

Osteolytic lesions (OL) characterize symptomatic multiple myeloma. The mechanisms of how
malignant plasma cells (PC) cause OL in one region while others show no signs of bone …

Chemotherapy is a primary treatment for esophageal squamous cell carcinoma (ESCC).
Resistance to chemotherapeutic drugs is an important hurdle to effective treatment …

Aberrations on TP53, either as deletions of chromosome 17p (del17p) or mutations, are
associated with poor outcome in multiple myeloma (MM), but conventional detection …

The tumour microenvironment (TME) plays a critical role in disease progression in multiple
myeloma (MM). This study aimed to present an atlas of MM‐TME in disease progression and …

Multiple myeloma (MM), the world's second most common hematologic malignancy, poses
considerable clinical challenges due to its aggressive progression and resistance to …

Abstract Today, Monoclonal Gammopathy of Undetermined Significance (MGUS) is known
as a plasma cell malignancy susceptible to evolving into the life-threatening stage, multiple …