Load dependency in force–length relations in isolated single cardiomyocytes

G Iribe, T Kaneko, Y Yamaguchi, K Naruse - Progress in biophysics and …, 2014 - Elsevier
The previously reported pressure–volume (PV) relationship in frog hearts shows that end-
systolic PV relation (ESPVR) is load dependent, whereas ESPVR in canine hearts is load …

[HTML][HTML] An automated system using spatial oversampling for optical mapping in murine atria. Development and validation with monophasic and transmembrane …

TY Yu, F Syeda, AP Holmes, B Osborne… - Progress in biophysics …, 2014 - Elsevier
We developed and validated a new optical mapping system for quantification of electrical
activation and repolarisation in murine atria. The system makes use of a novel 2nd …

Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition

VN Parikh, J Liu, C Shang, C Woods… - American Journal …, 2018 - journals.physiology.org
The G protein-coupled receptor APJ is a promising therapeutic target for heart failure.
Constitutive deletion of APJ in the mouse is protective against the hypertrophy-heart failure …

Interactions between mitral valve and left ventricle analysed by 2D speckle tracking in patients with mitral valve prolapse: one more piece to the puzzle

O Huttin, S Pierre, C Venner, D Voilliot… - European Heart …, 2017 - academic.oup.com
Aims Two-dimensional echocardiography often reveals abnormal left ventricle (LV) lateral
wall kinetics in patients presenting with mitral valve prolapse (MVP). However, relations …

Modulation of the contractility of micropatterned myocardial cells with nanoscale forces using atomic force microscopy

N Nagarajan, V Vyas, BD Huey… - …, 2016 - journals.sagepub.com
The ability to modulate cardiomyocyte contractility is important for bioengineering
applications ranging from heart disease treatments to biorobotics. In this study, we examined …

[HTML][HTML] Ranolazine-mediated attenuation of mechanoelectric feedback in atrial myocyte monolayers

I Del-Canto, L Gómez-Cid… - Frontiers in …, 2020 - frontiersin.org
Background Mechanical stretch increases Na+ inflow into myocytes, related to mechanisms
including stretch-activated channels or Na+/H+ exchanger activation, involving Ca2+ …

Mechanisms and clinical management of ventricular arrhythmias following blunt chest trauma

DH Wolbrom, A Rahman… - … Research and Practice, 2016 - Wiley Online Library
Nonpenetrating, blunt chest trauma is a serious medical condition with varied clinical
presentations and implications. This can be the result of a dense projectile during …

[PDF][PDF] 18F-氟代脱氧葡萄糖心肌代谢显像探测左心室室壁瘤的存活心肌及其合并室性心律失常对患者长期预后的影响

杨易剑, 侯翠红, 田丛娜, 王伟学, 魏红星, 赵敏, 郭风… - 中国循环杂志, 2015 - nccd.org.cn
摘要目的: 评估左心室室壁瘤部位存活心肌和室性心律失常对室壁瘤患者预后的影响. 方法:
研究纳入160 例左心室室壁瘤患者. 所有患者均行99Tcm-甲氧基异丁基异腈(MIBI) …

[HTML][HTML] Integrative Cardiovascular Physiology and Pathophysiology: Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and …

VN Parikh, J Liu, C Shang, C Woods… - American Journal of …, 2018 - ncbi.nlm.nih.gov
The G protein-coupled receptor APJ is a promising therapeutic target for heart failure.
Constitutive deletion of APJ in the mouse is protective against the hypertrophy-heart failure …

Sistema automatizado para estimulação elétrica e avaliação da dinâmica do cálcio intracelular em cardiomiócitos derivados de células-tronco pluripotentes induzidas …

DM Veronez - 2018 - teses.usp.br
Este estudo apresenta o desenvolvimento e validação de uma nova abordagem para a
avaliação do cálcio intracelular em culturas de cardiomiócitos derivados de células-tronco …