Cutibacterium acnes as an Opportunistic Pathogen: An Update of Its Virulence-Associated Factors

C Mayslich, PA Grange, N Dupin - Microorganisms, 2021 - mdpi.com
Cutibacterium acnes is a member of the skin microbiota found predominantly in regions rich
in sebaceous glands. It is involved in maintaining healthy skin and has long been …

Standard classification and pathophysiology of rosacea: the 2017 update by the National Rosacea Society Expert Committee

RL Gallo, RD Granstein, S Kang, M Mannis… - Journal of the American …, 2018 - Elsevier
In 2002, the National Rosacea Society assembled an expert committee to develop the first
standard classification of rosacea. This original classification was intended to be updated as …

TREM2 macrophages induced by human lipids drive inflammation in acne lesions

TH Do, F Ma, PR Andrade, R Teles… - Science …, 2022 - science.org
Acne affects 1 in 10 people globally, often resulting in disfigurement. The disease involves
excess production of lipids, particularly squalene, increased growth of Cutibacterium acnes …

Host-microbiome interactions and recent progress into understanding the biology of acne vulgaris

AM O'Neill, RL Gallo - Microbiome, 2018 - Springer
Acne is one of the most common skin diseases worldwide and results in major health care
costs and significant morbidity to severely affected individuals. However, the …

Acne vulgaris

SM Tuchayi, E Makrantonaki, R Ganceviciene… - Nature reviews Disease …, 2015 - nature.com
Acne vulgaris is a chronic inflammatory disease—rather than a natural part of the life cycle
as colloquially viewed—of the pilosebaceous unit (comprising the hair follicle, hair shaft and …

Sebaceous immunobiology-skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations

CC Zouboulis, T Coenye, L He, K Kabashima… - Frontiers in …, 2022 - frontiersin.org
This review presents several aspects of the innovative concept of sebaceous
immunobiology, which summarizes the numerous activities of the sebaceous gland …

[HTML][HTML] The role of inflammation in the pathology of acne

EA Tanghetti - The Journal of clinical and aesthetic dermatology, 2013 - ncbi.nlm.nih.gov
The conventional perspective of acne pathogenesis holds that Propionibacterium acnes
colonizes the duct of the sebaceous follicle, causing an innate immune response and the …

Propionibacterium acnes: an update on its role in the pathogenesis of acne

C Beylot, N Auffret, F Poli, JP Claudel… - Journal of the …, 2014 - Wiley Online Library
In recent years, significant progress has been made in the understanding of the
pathophysiological mechanisms of acne and the role of Propionibacterium acnes. With this …

Acne is an inflammatory disease and alterations of sebum composition initiate acne lesions

CC Zouboulis, E Jourdan… - Journal of the European …, 2014 - Wiley Online Library
Hyperseborrhoea has been considered as a major aetiopathogenetic factor of acne.
However, changes in sebaceous gland activity not only correlate with seborrhoea but also …

Standard management options for rosacea: The 2019 update by the National Rosacea Society Expert Committee

D Thiboutot, R Anderson, F Cook-Bolden… - Journal of the American …, 2020 - Elsevier
In 2017, a National Rosacea Society Expert Committee developed and published an
updated classification of rosacea to reflect current insights into rosacea pathogenesis …