Osteoporosis is a bone disorder with remarkable changes in bone biologic material and
consequent bone structural distraction, affecting millions of people around the world from …

Osteoporosis, defined by the World Health Organization (WHO) as a bone mineral density
(BMD) T-score less than-2.5 as measured by dual-emission x-ray absorptiometry (DXA) is a …

Osteoporosis is a disorder in which loss of bone strength leads to fragility fractures. This
review examines the fundamental pathogenetic mechanisms underlying this disorder, which …

Osteoporosis is a major concern all over the world. With aging, a gradual loss of bone mass
results in osteopenia and osteoporosis. Heritable factors account for 60–80% of optimal …

Osteoporosis is a common disease with a strong genetic component characterized by
reduced bone mass and increased risk of fragility fractures. Twin and family studies have …

Background The genetic impact on the causation of osteoporotic fractures is unclear. A large
twin study is ideally suited to determine the genetic liability to categories of fracture at …

To identify and validate genes associated with bone mineral density (BMD), which is a
prominent osteoporosis risk factor, we tested 379,319 SNPs in 1000 unrelated white US …

Bone loss in the lower extremities and lumbar spine is an established consequence of long-
duration human space flight. Astronauts typically lose as much bone mass in the proximal …

Background: Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease
caused by mutations in sarcomeric genes. However, extensive genetic screening failed to …

Purpose The dietary inflammatory index (DII) is a scoring system to quantify the inflammatory
effects of nutrients and foods. Inflammation may affect bone health. The purpose of this study …