Polycyclic aromatic hydrocarbon and its effects on human health: An overeview

MA Mallah, L Changxing, MA Mallah, S Noreen, Y Liu… - Chemosphere, 2022 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are a class of chemicals of considerable
environmental significance. PAHs are chemical contaminants of fused carbon and hydrogen …

Benzo[a]pyrene—Environmental Occurrence, Human Exposure, and Mechanisms of Toxicity

B Bukowska, K Mokra, J Michałowicz - International journal of molecular …, 2022 - mdpi.com
Benzo [a] pyrene (B [a] P) is the main representative of polycyclic aromatic hydrocarbons
(PAHs), and has been repeatedly found in the air, surface water, soil, and sediments. It is …

Molecular mechanisms of action of selected substances involved in the reduction of benzo [a] pyrene-induced oxidative stress

B Bukowska, P Duchnowicz - Molecules, 2022 - mdpi.com
Benzo [a] pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) primarily formed by
burning of fossil fuels, wood and other organic materials. BaP as group I carcinogen shows …

Modulation of CYP1A1 metabolism: From adverse health effects to chemoprevention and therapeutic options

M Mescher, T Haarmann-Stemmann - Pharmacology & therapeutics, 2018 - Elsevier
The human cytochrome P450 (CYP) 1A1 gene encodes a monooxygenase that metabolizes
multiple exogenous and endogenous substrates. CYP1A1 has become infamous for its …

Precarcinogens in food–Mechanism of action, formation of DNA adducts and preventive measures

B Bukowska, P Duchnowicz, TB Tumer, J Michałowicz… - Food Control, 2023 - Elsevier
Food quality and food composition play key roles in human health. Food may contain
harmful ingredients apart from the basic ingredients beneficial to our body. A harmful group …

Exposure to polycyclic aromatic hydrocarbons: bulky DNA adducts and cellular responses

F Henkler, K Stolpmann, A Luch - Molecular, Clinical and Environmental …, 2012 - Springer
Environmental and dietary carcinogens such as polycyclic aromatic hydrocarbons (PAHs)
have been intensively studied for decades. Although the genotoxicity of these compounds is …

[HTML][HTML] Polycyclic aromatic hydrocarbons

H Choi, R Harrison, H Komulainen… - WHO guidelines for …, 2010 - ncbi.nlm.nih.gov
The term polycyclic organic matter (POM) defines a broad class of compounds that generally
includes all organic structures containing three or more fused aromatic rings. These …

A review of stable isotope labeling and mass spectrometry methods to distinguish exogenous from endogenous DNA adducts and improve dose–response …

K Lu, YC Hsiao, CW Liu, R Schoeny… - Chemical Research …, 2021 - ACS Publications
Cancer remains the second most frequent cause of death in human populations worldwide,
which has been reflected in the emphasis placed on management of risk from environmental …

Metabolically Competent Human Skin Models: Activation and Genotoxicity of Benzo[a]pyrene

J Brinkmann, K Stolpmann, S Trappe… - toxicological …, 2013 - academic.oup.com
The polycyclic aromatic hydrocarbon (PAH) benzo [a] pyrene (BP) is metabolized into a
complex pattern of BP derivatives, among which the ultimate carcinogen (+)-anti-BP-7, 8-diol …

Inhalation exposure and risk of polycyclic aromatic hydrocarbons (PAHs) among the rural population adopting wood gasifier stoves compared to different fuel-stove …

N Lin, Y Chen, W Du, G Shen, X Zhu, T Huang… - Atmospheric …, 2016 - Elsevier
Polycyclic aromatica hydrocarbons (PAHs) are a group of compounds with carcinogenic
potentials and residential solid fuel combustion is one major source of PAHs in most …