Deep learning on histopathological images for colorectal cancer diagnosis: a systematic review

A Davri, E Birbas, T Kanavos, G Ntritsos, N Giannakeas… - Diagnostics, 2022 - mdpi.com
Colorectal cancer (CRC) is the second most common cancer in women and the third most
common in men, with an increasing incidence. Pathology diagnosis complemented with …

An ensemble learning approach for enhanced classification of patients with hepatitis and cirrhosis

D Chicco, G Jurman - IEEE Access, 2021 - ieeexplore.ieee.org
Hepatitis C is an infectious disease that affects more than 70 million people worldwide, even
killing 400 thousand of them annually. To better understand this disease and its prognosis …

Digital image analysis of picrosirius red staining: A robust method for multi-organ fibrosis quantification and characterization

GE Courtoy, I Leclercq, A Froidure, G Schiano… - Biomolecules, 2020 - mdpi.com
Current understanding of fibrosis remains incomplete despite the increasing burden of
related diseases. Preclinical models are used to dissect the pathogenesis and dynamics of …

Unpaired virtual histological staining using prior-guided generative adversarial networks

R Yan, Q He, Y Liu, P Ye, L Zhu, S Shi, J Gou… - … Medical Imaging and …, 2023 - Elsevier
Fibrosis is an inevitable stage in the development of chronic liver disease and has an
irreplaceable role in characterizing the degree of progression of chronic liver disease …

Involvement of ferroptosis in diabetes-induced liver pathology

A Stancic, K Velickovic, M Markelic, I Grigorov… - International Journal of …, 2022 - mdpi.com
Cell death plays an important role in diabetes-induced liver dysfunction. Ferroptosis is a
newly defined regulated cell death caused by iron-dependent lipid peroxidation. Our …

Moringa oleifera mitigates ethanol-induced oxidative stress, fatty degeneration and hepatic steatosis by promoting Nrf2 in mice

CG Kim, SN Chang, SM Park, BS Hwang, SA Kang… - Phytomedicine, 2022 - Elsevier
Background Moringa oleifera (M. oleifera) is cultivated throughout the world and it is known
by numerous regional names and is consumed as medication for various diseases such as …

Mechanical regulation of mitochondrial dynamics and function in a 3D-engineered liver tumor microenvironment

A Frtús, B Smolková, M Uzhytchak… - ACS Biomaterials …, 2023 - ACS Publications
It has become evident that physical stimuli of the cellular microenvironment transmit
mechanical cues regulating key cellular functions, such as proliferation, migration, and …

Mangiferin relieves CCl4-induced liver fibrosis in mice

L Zhang, C Liu, L Yin, C Huang, S Fan - Scientific Reports, 2023 - nature.com
Hepatic fibrosis is a late stage process of many chronic liver diseases. Blocking the fibrosis
process will be beneficial to the treatment and recovery of the diseases. Mangiferin has …

Virtual liver needle biopsy from reconstructed three-dimensional histopathological images: Quantification of sampling error

Q Li, F Wang, Y Chen, H Chen, S Wu, AB Farris… - Computers in Biology …, 2022 - Elsevier
Introduction: Prevalently considered as the “gold-standard” for diagnosis of hepatic fibrosis
and cirrhosis, the clinical liver needle biopsy is known to be subject to inadequate sampling …

The role of WNT/β-catenin signaling pathway and glutamine metabolism in the pathogenesis of CCl4-induced liver fibrosis: repositioning of niclosamide and concerns …

NE El-Ashmawy, GM Al-Ashmawy, HE Fakher… - Cytokine, 2020 - Elsevier
Background Liver fibrosis is a serious health problem which may lead to advanced liver
cirrhosis and hepatocellular carcinoma. Objective The present study aimed to investigate the …