Background Changes in protein glycosylation are widely observed in tumor cells. N-glycan
branching through adding β1, 6-linked N-acetylglucosamine (β1, 6-GlcNAc) to an α1, 6 …

Gastric cancer is a remarkably heterogeneous tumor. Despite some advances in the
diagnosis and treatment of gastric cancer in recent years, the precise treatment and curative …

The N-glycans attached to proteins contain various GlcNAc branches, the aberrant formation
of which correlates with various diseases. N-Acetylglucosaminyltransferase-IVa (GnT-IVa or …

Over the past 3 decades, our group has been involved in studies related to the biosynthesis
of N-glycan branching and related glycosyltransferases and have purified most of these …

This review provides a detailed study of pancreatic cancer (PC) and the implication of
different types of cancers concerning diabetes. The combination of anti-diabetic drugs with …

A protecting-group-free method for synthesis of β-glycosyl esters and aryl β-glycosides was
developed by using latent chemical reactivity of N-acetyl-d-glucosamine (GlcNAc) oxazoline …

Structural variation of N-glycans is essential for the regulation of glycoprotein functions.
GalNAcβ1-4GlcNAc (LacdiNAc or LDN), a unique sub-terminal glycan structure synthesized …

UDP-Glc: glycoprotein glucosyltransferase (UGGT) has a central role to retain quality control
of correctly folded N-glycoprotein in the endoplasmic reticulum (ER). A selective and potent …

22. De La Cruz LK, Yang X, Menshikh A, Brewer M, Lu W, Wang M, Wang S, Ji X, Cachuela
A, Yang H, Gallo D, Tan C, Otterbein L, de Caestecker M, Wang B. Adapting decarbonylation …

Correct elaboration of N-linked glycans in the secretory pathway of human cells is essential
in physiology. Early N-glycan biosynthesis follows an assembly line principle before …