As a greater proportion of patients survive their initial cardiac insult, medical systems
worldwide are being faced with an ever-growing need to understand the mechanisms …

Sepsis is a major health problem worldwide. As the number of sepsis cases increases, so
does the number of sepsis survivors who suffer from" post-sepsis syndrome" after hospital …

Objectives: This study sought to evaluate the safety and efficacy of rosuvastatin in preventing
contrast-induced acute kidney injury (CI-AKI) in patients with diabetes mellitus (DM) and …

Importance Observational studies have reported that statin use may be associated with
improved outcomes of various infections. Ventilator-associated pneumonia (VAP) is the most …

Background Atherosclerosis and sepsis share several pathophysiological similarities,
including immune dysregulation, increased thrombogenesis, and systemic inflammation …

Sepsis, an infection-induced inflammatory syndrome, is a leading and increasing cause of
mortality worldwide. Animal and human observational studies suggest statins may prevent …

PURPOSE: The aim of this study was to systematically review the literature on the effect of
statins on mortality in patients with infection and/or sepsis. MATERIALS AND METHODS …

Endothelial nitric oxide synthase (eNOS, NOS3) is responsible for producing nitric oxide
(NO)—a key molecule that can directly (or indirectly) act as a vasodilator and anti …

Background. Myocardial depression in sepsis is common, and it is associated with higher
mortality. In recent years, the hypothesis that the myocardial dysfunction during sepsis could …

Sepsis occurs when the immune system responds to a localised infection at a systemic level,
thereby causing tissue damage and organ dysfunction. Statins have proven health benefits …