Preeclampsia (PE) affects 5‐8% of pregnant women, and it is the major cause of perinatal
morbidity and mortality. It is defined as arterial hypertension in women after 20 weeks of …

BACKGROUND Pre-eclampsia has a clear familial component, suggesting that the condition
may be partly attributable to genetic susceptibility. The search for susceptibility genes has …

Background Preeclampsia is a severe complication of pregnancy characterized by an
excessive maternal systemic inflammatory response with activation of both the innate and …

Background: Preeclampsia (PE) is a syndromic disorder that affects 2% to 8% of
pregnancies and is diagnosed principally when hypertension appears in the second-d half …

Inflammation may play a major role in the pathogenesis of preeclampsia (PE). In this meta-
analysis, we determined whether maternal polymorphisms and serum concentrations of …

Preeclampsia is a multi‐system hypertensive disorder of pregnancy, with significant rates of
maternal and neonatal morbidity. It represents a major cause of preterm birth, as definitive …

The purpose of this study was to determine whether increased serum soluble fms-like
tyrosine kinase-1 (sFlt-1) and decreased placental growth factor (PlGF) levels in pre …

Severe preeclampsia is a common cause of maternal and perinatal morbidity worldwide.
The disease clusters in families; however, individual genetic studies have produced …

Introduction Preeclampsia (PE) is a multi-system disorder of pregnancy characterized by
hypertension and proteinuria. Healthy pregnancy is associated with a controlled …

Placental vascularization is a tightly regulated physiological process in which the maternal
immune system plays a fundamental role. Vascularization of the maternal-placental interface …