Significance: The oxidative stress, resulting from an imbalance in the production and
scavenging of reactive oxygen species (ROS), is known to be involved in the development …

Diabetic nephropathy (DN) is one of the serious complications of diabetes mellitus, primarily
arising from type 2 diabetes (T2DM), and can progress to chronic kidney disease (CKD) and …

The nucleotide-binding oligomerization domain (NOD)-like receptor protein 3 (NLRP3)
inflammasome plays an important role in microglia-mediated inflammation. Dysregulation of …

The main function of NADPH oxidases is to catalyse the formation of reactive oxygen
species (ROS). NADPH oxidase 4 (NOX4) is expressed at high levels in kidney tubular cells …

A novel series of analogues based on 5-(1-(4-chloro-3-methoxyphenyl) piperidin-4-yl)-4-
phenyl-2 H-1, 2, 4-triazole-3 (4 H)-thione core have been synthesized and their potential as …

Background Plants have always played important role in treating human and animal
diseases as a therapeutic agent for traditional medicine. Through extensive research …

The investigation of facial synthetic methods for chemical synthesis is a growing area of
interest due to increasing environmental issues. The use of catalysts in organic reactions …

Chronic obstructive pulmonary disease (COPD) is a very common and frequently fatal
airway disease. Current therapies for COPD depend mainly on long-acting bronchodilators …

The investigation of methods for the chemical synthesis is a growing area of interest due to
increasing environmental issues. The use of catalysts in organic reactions has gained …

Chiral considerations are found to be very much relevant in various aspects of forensic
toxicology and pharmacology. In forensics, it has become increasingly important to identify …