Nanodiscs: Game changer nano-therapeutics and structural biology tools
In recent years, engineering biocompatible HDL nanodiscs has garnered a great interest
with wide applications for for both drug delivery and structural biology. In this review, we …
with wide applications for for both drug delivery and structural biology. In this review, we …
Huntington's disease: complex pathogenesis and therapeutic strategies
H Tong, T Yang, S Xu, X Li, L Liu, G Zhou… - International Journal of …, 2024 - mdpi.com
Huntington's disease (HD) arises from the abnormal expansion of CAG repeats in the
huntingtin gene (HTT), resulting in the production of the mutant huntingtin protein (mHTT) …
huntingtin gene (HTT), resulting in the production of the mutant huntingtin protein (mHTT) …
[HTML][HTML] Systemic delivery of mutant huntingtin lowering antisense oligonucleotides to the brain using apolipoprotein AI nanodisks for Huntington disease
Efficient delivery of therapeutics to the central nervous system (CNS) remains a major
challenge for the treatment of neurological diseases. Huntington disease (HD) is a …
challenge for the treatment of neurological diseases. Huntington disease (HD) is a …