Genomic instability can initiate cancer, augment progression, and influence the overall
prognosis of the affected patient. Genomic instability arises from many different pathways …

Adequate resection margins are critical to the treatment decisions and prognosis of patients
with head and neck squamous cell carcinoma (HNSCC). However, there are numerous …

Head and neck squamous cell carcinomas (HNSCCs) are the most devastating diseases in
India and southeast Asia. It is a preventable and curable disease if detected early. Tobacco …

Background The purpose of this study was to investigate the prognostic value of the
pretreatment inflammatory markers platelet‐to‐lymphocyte ratio (PLR) and the neutrophil‐to …

Mitochondria control essential cellular activities including generation of ATP via oxidative
phosphorylation. Mitochondrial DNA (mtDNA) mutations in the regulatory D-loop region and …

There is a complete lack of highly sensitive and specific biomarkers for early pancreatic
ductal adenocarcinoma (PDAC) diagnosis, limiting multi-modal therapeutic options …

Mitochondria from normal and cancerous cells represent a tale of two cities, wherein both
execute similar processes but with different cellular and molecular effects. Given the number …

Background Recent studies have reported a relationship between prognosis and neutrophil-
to-lymphocyte ratio (NLR) in patients with head and neck cancer (HNC). As the results are …

Head and neck squamous cell carcinoma (HNSCC) is a molecularly heterogeneous
disease, with a 5-year survival rate that still hovers at~ 60% despite recent advancements …

Mitochondrial DNA (mtDNA) mutations were reported in different cancers. However, the
nature and role of mtDNA mutation in never‐smoker lung cancer patients including patients …