Osteoarthritis: pathogenic signaling pathways and therapeutic targets

Q Yao, X Wu, C Tao, W Gong, M Chen, M Qu… - Signal transduction and …, 2023 - nature.com
Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

Exercise/physical activity and health outcomes: an overview of Cochrane systematic reviews

P Posadzki, D Pieper, R Bajpai, H Makaruk… - BMC public health, 2020 - Springer
Background Sedentary lifestyle is a major risk factor for noncommunicable diseases such as
cardiovascular diseases, cancer and diabetes. It has been estimated that approximately 3.2 …

[PDF][PDF] Clinical management of COVID-19: living guideline, 13 January 2023

World Health Organization - 2023 - apps.who.int
Post COVID-19 condition occurs in individuals with a history of probable or confirmed SARS-
CoV-2 infection, usually 3 months from the onset of COVID-19 with symptoms that last for at …

[HTML][HTML] An updated algorithm recommendation for the management of knee osteoarthritis from the European Society for Clinical and Economic Aspects of …

O Bruyère, G Honvo, N Veronese, NK Arden… - Seminars in arthritis and …, 2019 - Elsevier
Abstract Objectives The European Society for Clinical and Economic Aspects of
Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) sought to revisit the …

Benefits and mechanisms of exercise training for knee osteoarthritis

CY Zeng, ZR Zhang, ZM Tang, FZ Hua - Frontiers in physiology, 2021 - frontiersin.org
Knee osteoarthritis is a chronic degenerative disease. Cartilage and subchondral bone
degeneration, as well as synovitis, are the main pathological changes associated with knee …

Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews

LJ Geneen, RA Moore, C Clarke… - Cochrane database …, 2017 - cochranelibrary.com
Background Chronic pain is defined as pain lasting beyond normal tissue healing time,
generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep …

Exercise interventions and patient beliefs for people with hip, knee or hip and knee osteoarthritis: a mixed methods review

M Hurley, K Dickson, R Hallett, R Grant… - Cochrane Database …, 2018 - cochranelibrary.com
Background Chronic peripheral joint pain due to osteoarthritis (OA) is extremely prevalent
and a major cause of physical dysfunction and psychosocial distress. Exercise is …

[HTML][HTML] Osteoarthritis year in review 2017: clinical

AE Nelson - Osteoarthritis and cartilage, 2018 - Elsevier
This review is based on a systematic review of the literature relevant to clinical topics in
osteoarthritis (OA) performed for the time period February 22, 2016 to April 1, 2017. A …

[HTML][HTML] OARSI guidelines for the non-surgical management of knee osteoarthritis

TE McAlindon, RR Bannuru, MC Sullivan… - Osteoarthritis and …, 2014 - Elsevier
Objective To develop concise, up-to-date, patient-focused, evidence-based, expert
consensus guidelines for the management of knee osteoarthritis (OA), intended to inform …

Effective treatment options for musculoskeletal pain in primary care: a systematic overview of current evidence

OO Babatunde, JL Jordan, DA Van der Windt, JC Hill… - PloS one, 2017 - journals.plos.org
Background & aims Musculoskeletal pain, the most common cause of disability globally, is
most frequently managed in primary care. People with musculoskeletal pain in different body …