Preventing and controlling influenza virus infection remains a global public health
challenge, as it causes seasonal epidemics to unexpected pandemics. These infections are …

With more than 5 million fatalities and close to 300 million reported cases, COVID-19 is the
first documented pandemic due to a coronavirus that continues to be a major health …

A single gene yields many forms of proteins via combinations of posttranscriptional/
posttranslational modifications. Proteins also fold into higher‐order structures and interact …

Viroporins possess important potential as antiviral targets due to their critical roles during
virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine …

The influenza A M2 homotetrameric channel consists of four transmembrane (TM) and four
amphipathic helices (AHs). This viral proton channel is suggested to form clusters in the …

Membrane proteins represent the majority of clinical drug targets and are actively involved in
a range of cellular processes. However, the complexity of membrane mimetics for …

Lipid membranes have recently been implicated in protein misfolding and disease etiology,
including for α-synuclein and Parkinson's disease. However, studying the intersection of …

Viroporins constitute a class of viral membrane proteins with diverse roles in the viral life
cycle. They can self-assemble and form pores within the bilayer that transport substrates …

Membrane proteins have evolved to work optimally within the complex environment of the
biological membrane. Consequently, interactions with surrounding lipids are part of their …

Many membrane proteins form functional complexes that are either homo-or hetero-
oligomeric. However, it is challenging to characterize membrane protein oligomerization in …