DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

The physicochemical nature of DNA allows the assembly of highly predictable structures via
several fabrication strategies, which have been applied to make breakthroughs in various …

RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

Cancer, infectious diseases, and metabolic and hereditary genetic disorders are a global
health burden affecting millions of people, with contemporary treatments offering limited …

Recently, DNA nanostructures with vast application potential in the field of biomedicine,
especially in drug delivery. Among these, tetrahedral DNA nanostructures (TDN) have …

The targeted delivery of chemotherapeutic drugs is a major challenge in the clinical
treatment of cancer. Herein, we constructed a multifunctional DNA nanoplatform as a …

Drug resistance is a major obstacle to the efficient therapy of drug-resistant cancer. To
overcome this problem, we constructed a multifunctional DNA origami-based nanocarrier for …

A three-dimensional DNA tetrahedral nanostructure is constructed to support a walker strand
on top and multiple track strands around it via the assembly of triplex-forming …

In order to cure diseases efficiently with minimal side effects in sophisticated medicine,
eminent drugs must be selectively delivered to diseased parts and allow to work only there …

DNA not only plays a vital role in nature as fundamental hereditary material for storing
genetic material, but also serves as well-defined functional material, for example, building …